Results 181 to 190 of about 833,948 (273)

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

open access: yesAdvanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue   +15 more
wiley   +1 more source

The Management of Pain [PDF]

open access: bronze, 1994
Richard Lansdown
openalex   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

open access: yesAdvanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang   +12 more
wiley   +1 more source

Uncovering bias: sex disparities in pain management. [PDF]

open access: yesAnn Med Surg (Lond)
Asif M, Asif A, Rahman UA, Jaber MH.
europepmc   +1 more source

Chronic low back pain in primary care: a prospective study on the management and course [PDF]

open access: bronze, 1998
Maurits W. van Tulder   +3 more
openalex   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

Evidence summary on pain management in thoracoscopic lung cancer surgery. [PDF]

open access: yesAsia Pac J Oncol Nurs
Wu D   +7 more
europepmc   +1 more source

Attitudes of veterinary medical students, house officers, clinical faculty, and staff toward pain management in animals [PDF]

open access: bronze, 1999
Peter W. Hellyer   +4 more
openalex   +1 more source

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