Results 61 to 70 of about 833,948 (273)
Machine Learning Study of the Extended Drug-target Interaction Network informed by Pain Related Voltage-Gated Sodium Channels [PDF]
arXiv, 2023 Pain is a significant global health issue, and the current treatment options for pain management have limitations in terms of effectiveness, side effects, and potential for addiction. There is a pressing need for improved pain treatments and the development of new drugs.
arxiv
Arthritis Care &Research, EarlyView.Objective Targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) have expanded the management of autoimmune diseases, including rheumatic diseases. As the use of these drugs grows, it is important to understand their effects on pregnancy.
Vienna Cheng +7 more
wiley +1 more source
BMJ Open, 2020 Introduction At the conception of this study (January 2019), a literature search by the authors found no evidence-based or consensus perioperative guidelines for patients consuming cannabis products, or for those patients in whom a cannabinoid medication
Joseph Fiorellino +4 more
doaj +1 more source
Anesthesiology Research and Practice, 2021 Background. Emotional and psychological effects following abortion are more common than physical side effects and can range from mild regret to more serious complications such as depression.
Raham Hasan Mostafa +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and fatigue. Almost everyone with fibromyalgia has sleep problems. We aimed to evaluate the effectiveness and safety of current interventions for the management of fibromyalgia‐related sleep problems.
Jemma Hudson +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell +10 more
wiley +1 more source
"It's Sink or Swim'': Exploring Patients' Challenges and Tool Needs for Self-Management of Postoperative Acute Pain [PDF]
Poorly managed postoperative acute pain can have long-lasting negative impacts and pose a major healthcare issue. There is limited investigation to understand and address the unique needs of patients experiencing acute pain. In this paper, we tackle this gap through an interview study with 14 patients who recently underwent postoperative acute pain to ...
arxiv +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf +6 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew +6 more
wiley +1 more source