Results 121 to 130 of about 929,846 (313)

Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer. [PDF]

open access: yes, 2019
In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours before
Buyyounouski, Mark K   +9 more
core  

How Do We Understand Depression in People with Persistent Pain? [PDF]

open access: yes, 2016
Depression and depressed mood are common in people with persistent (chronic) pain, exacerbating disability and worsening quality of life. Yet the relationship between persistent pain and depression remains unclear, despite its importance for designing or
Schafer, G, Williams, AC
core   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Effects of eugenol on pain response to the formalin test and plasma antioxidant activity in high fructose drinking water in male rats

open access: yesInternational Journal of Preventive Medicine, 2019
Background: Increased consumption of fructose in recent years has increased the risk of developing metabolic syndrome. In this syndrome, induction of oxidative stress, cellular dysfunction, and decrease of antioxidant capacity can change response to pain.
Omid Ghofran   +2 more
doaj   +1 more source

The Comparison of Gabapentin and Amitriptilin Effectivity as Pain Therapy in Herniated Nucleus Pulposus [PDF]

open access: yes, 2015
Herniated nucleus pulposus (HNP) is one of peripheral neuropathic pain. Although concensus guidelines for the treatment of neuropathic pain are based on the results of the RCT studies, there are still gaps in the literatures.
Cahyaningsih, I. (Indriastuti)   +2 more
core  

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

open access: yesArthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla   +13 more
wiley   +1 more source

Treinamento com natação sobre a avaliação funcional da nocicepção ciática em ratos Swimming training and functional assessment of sciatic nociception in rats

open access: yesRevista Brasileira de Reumatologia, 2011
INTRODUÇÃO: Existe certa controvérsia com relação ao efeito protetor do exercício em indivíduos com neuropatia periférica. OBJETIVO: Avaliar o treinamento físico, moderado e com intensidade progressiva, como fator infl uenciador da nocicepção em ratos ...
Gladson Ricardo Flor Bertolini   +4 more
doaj   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg   +26 more
wiley   +1 more source

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