Results 51 to 60 of about 5,652,392 (296)

Long-Term Effectiveness of Intradiscal Culture-Expanded Mesenchymal Stem Cells (MSCs) with Platelet Products for Discogenic Low Back Pain

Biomedicines
Background/Objectives: Low back pain (LBP) remains one of the leading causes of disability globally and contributes significantly to healthcare expenditures. Discogenic LBP, a subtype stemming from intervertebral disc degeneration, often provesrefractory
Nicholas Hooper, Joseph Ierulli, Chase Demarest, John Pitts, Oluseun A. Olufade, Christopher Williams   +5 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pain Medicine Fellowship Program Websites in the United States of America – A Nonparametric Statistic Analysis of 14 Different Criteria

Journal of Pain Research, 2021
Sahil Gupta,1 Scott Palmer,2 Guilherme Ferreira-Dos-Santos,3,4 Mark Friedrich Hurdle2 1Department of Pain Medicine, Southern Illinois Healthcare, Carbondale, IL, USA; 2Department of Pain Medicine, Mayo Clinic, Jacksonville, FL, USA; 3Department of ...
Gupta S, Palmer S, Ferreira-Dos-Santos G, Hurdle MF   +3 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Teaching Chronic Pain in the Family Medicine Clerkship: Influences of Experience and Beliefs About Treatment Effectiveness: A CERA Study [PDF]

, 2016
BACKGROUND: Chronic pain is a common and important disease state in North America, but many medical students and practicing physicians feel poorly prepared to treat this condition._x000D_ METHODS: Data were collected via the 2014 CERA Family Medicine ...
Zoberi, Kimberly Schiel, Antoun, Jumana M., Everard, Kelly M.   +2 more
core  

Pain Management for Primary Care Providers: A Narrative Review of High-Impact Studies, 2014–2016

, 2017
Objective: This manuscript reviews high-impact, peer-reviewed studies published from January 2014 to March 2016 that are relevant to pain management in primary care.
Becker, William C., Michael Picchioni, Bair, Matthew J., Picchioni, Michael, Matthew J Bair, William C Becker, Joanna L Starrels, Frank, Joseph W., Joseph W Frank, Starrels, Joanna L.   +9 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The effects of yoga on patients chronic pain [PDF]

, 2004
Plan BChronic pain is a challenging and costly medical problem. Interest has increased in the use of complementary alternative medicine (CAM) as a cost-effective way to manage chronic pain. The present program was initiated to assess the effects of Hatha
Young, Constance M.
core  

Informed Consent for Spine Procedures: Best Practice Guideline from the American Society of Pain and Neuroscience (ASPN)

Journal of Pain Research, 2023
Timothy Deer,1 Ankur A Patel,2 Dawood Sayed,3 Ashley Bailey-Classen,4 Ashley Comer,1 Benjamin Gill,5 Kiran Patel,6 Alaa Abd-Elsayed,7 Natalie Strand,8 Jonathan M Hagedorn,9 Zohra Hussaini,3 Nasir Khatri,10 Ryan Budwany,1 Melissa Murphy,11 Dan Nguyen,12 ...
Deer T, Patel AA, Sayed D, Bailey-Classen A, Comer A, Gill B, Patel K, Abd-Elsayed A, Strand N, Hagedorn JM, Hussaini Z, Khatri N, Budwany R, Murphy M, Nguyen D, Orhurhu V, Rabii M, Beall D, Hochschuler S, Schatman ME, Lubenow T, Guyer R, Raslan AM   +22 more
doaj