Results 141 to 150 of about 2,582,390 (433)

Pain Intensity Estimation from Mobile Video Using 2D and 3D Facial Keypoints [PDF]

open access: yesarXiv, 2020
Managing post-surgical pain is critical for successful surgical outcomes. One of the challenges of pain management is accurately assessing the pain level of patients. Self-reported numeric pain ratings are limited because they are subjective, can be affected by mood, and can influence the patient's perception of pain when making comparisons.
arxiv  

Endogenous Opioid Activity in the Anterior Cingulate Cortex Is Required for Relief of Pain

open access: yesJournal of Neuroscience, 2015
Pain is aversive, and its relief elicits reward mediated by dopaminergic signaling in the nucleus accumbens (NAc), a part of the mesolimbic reward motivation pathway. How the reward pathway is engaged by pain-relieving treatments is not known. Endogenous
E. Navratilova   +9 more
semanticscholar   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

Measuring Pain in Sickle Cell Disease using Clinical Text [PDF]

open access: yesarXiv, 2020
Sickle Cell Disease (SCD) is a hereditary disorder of red blood cells in humans. Complications such as pain, stroke, and organ failure occur in SCD as malformed, sickled red blood cells passing through small blood vessels get trapped. Particularly, acute pain is known to be the primary symptom of SCD.
arxiv  

Pain [PDF]

open access: yes
Painkilling drugs produce a good called relief which reduces the fixed level of bad (pain) the individual is endowed with. These drugs have the side-effect of reducing the utility the individual gets from consuming goods. This means that the shadow price
Filip Palda
core  

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

open access: yesAdvanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin   +21 more
wiley   +1 more source

Combined percutaneous radiofrequency ablation and cementoplasty for the treatment of extraspinal painful bone metastases: A prospective study

open access: yesJournal of the Egyptian National Cancer Institute, 2018
Introduction: About 50% of patients with cancer develop bone metastasis mainly presenting with distressing, drug-resistant pain. Aim of the work: The study evaluated efficacy and safety of combined cementoplasty and bony radiofrequency ablation in ...
Andrew Fares   +4 more
doaj  

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Gamma‐aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study

open access: yesNeuropsychopharmacology Reports, 2018
Aim Cancer pain impairs not only physical functions but also social functions and roles. Consequently, the overall health‐related quality of life of patients with cancer pain deteriorates. Opioid analgesics are recommended for treating moderate to strong
Yaeko Yokoshima   +11 more
doaj   +1 more source

Stress-induced hyperalgesia instead of analgesia in patients with chronic musculoskeletal pain [PDF]

open access: yesarXiv, 2019
Many individuals with chronic musculoskeletal pain (CMP) show impairments in their pain-modulatory capacity. Although stress plays an important role in chronic pain, it is not known if stress-induced analgesia (SIA) is affected in patients with CMP. We investigated SIA in 22 patients with CMP and 18 pain-free participants.
arxiv  

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