Results 221 to 230 of about 2,582,390 (433)
Advanced Science, EarlyView.How locus coeruleus noradrenergic‐spinal projections and subsequent α2A adrenoceptors‐CaMKII signaling cascades contribute to electroacupuncture‐induced antinociception in postoperative pain in mice is described. Abstract Postoperative pain remains a significant challenge in healthcare.
Wen‐Guang Chu +13 more
wiley +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
WEST LONDON HOSPITAL. ACUTE GLAUCOMA ; IRIDECTOMY; RELIEF OF PAIN, AND IMPROVEMENT OF VISION [PDF]
E HART
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EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation
Advanced Science, EarlyView.Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi +12 more
wiley +1 more source
Metabolism of sphingolipids in a rat spinal cord stenosis model
Biochemistry and Biophysics ReportsBackground: Lumbar spinal canal stenosis (LSCS) plays a crucial role in neurogenic claudication and neuropathic pain. Recent studies suggest that changes in sphingolipid metabolism are linked to neuropathic pain.
Baasanjav Uranbileg +6 more
doaj
RUPTURE OF THE STOMACH. RELIEF OF THE PAIN BY OPIUM. [PDF]
Wm.Edward Crowfoot
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Saline frontal lobotomy for the relief of pain [PDF]
, 1962 Raeburn C. Llewellyn, Charles B. Wilson
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Advanced Science, EarlyView.Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo +20 more
wiley +1 more source