Results 231 to 240 of about 782,118 (350)

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Comparison of the Effectiveness of Fascia Iliaca Compartment Block for Preoperative Pain Relief in Patients With Intracapsular or Extracapsular Hip Fractures. [PDF]

Geriatr Orthop Surg Rehabil
Stenvers E, Dijkerman L, Schop BPA, Nijholt IM, Munnik-Hagewoud R, Zuurmond RG.   +5 more
europepmc   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

Advanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui, Neela K. Codadu, Daman Rathore, Guanghui Li, Marcello Meneghetti, Anders L. Bøcker, Rune W. Berg, Rob C. Wykes, Christos Markos   +8 more
wiley   +1 more source

Long-term outcomes of total lumbar disc prosthesis: Sustained pain relief. [PDF]

N Am Spine Soc J
Vanaclocha V, Jordá-Gómez P, Saiz-Sapena N, Martínez-Leon J, Vanaclocha L.   +4 more
europepmc   +1 more source

Ultrasound Guided Quadratus Lumborum Block versus Patient Controlled Analgesia for Pain Relief after Cesarean Delivery. [PDF]

Osama Ali EI-Kelany, H.A. Hamza, Khaled Mohamed Gaballah, Rania Mahmoud Elsheikh, Sherif Sobhy Menshawy Khalifa   +4 more
openalex   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Comparing ethyl chloride and 10% lignocaine spray for pediatric intravenous cannulation pain relief. [PDF]

Clin Exp Pediatr
Vellanki S, Kulkarni M, Kumar HDA, Shetty D, Karthik B N, Tom M.   +5 more
europepmc   +1 more source

Preliminary experience with transversus abdominis plane block for postoperative pain relief in infants and children

, 2009
JosephD Tobias
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Extended osteoarthritis pain relief with neosaxitoxin using alginate-core polymeric microparticles.

Nanoscale
Zhang H, Baby HM, Ishihara S, Zhang C, Li J, Adamczyk NS, Cohen EM, Miller RE, Bajpayee AG.   +8 more
europepmc   +1 more source