The Experience of Living With Breast Cancer and the Assessment of Needs and Expectations
Journal of Patient Experience, 2021 Living with a chronic disease constitutes a biographical reversal characterized by change and loss. The aims of this study are to conceptualize the meaning of breast cancer, of its burden, to explore the patient's needs and expectations while being ...
Maria Nikoloudi MD +4 more
doaj +1 more source
Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain [PDF]
Pharmacological Research. 104750 (2020), 2020 Pepducins are cell-penetrating, membrane-tethered lipopeptides designed to target the intracellular region of a G protein-coupled receptor (GPCR) in order to allosterically modulate the receptor's signaling output. In this proof-of-concept study, we explored the pain-relief potential of a pepducin series derived from the first intracellular loop of ...
arxiv +1 more source
Comparison of Two Doses of Chloroprocaine for Spinal Anaesthesia in Brachytherapy Procedures: A Randomised Clinical Study [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Subarachnoid block is a widely used anaesthetic technique for lower abdominal and lower limb surgeries. Commonly used local anaesthetics are with longer duration of action and delayed recovery. Chloroprocaine is good choice for day care
Shashidhar Gowdra Sugandarajappa +2 more
doaj +1 more source
BMC Anesthesiology, 2018 Background While opioids are the mainstay for post-operative analgesia after lower segment caesarean section, they are associated with various untoward effects.
Ashok Jadon +7 more
doaj +1 more source
Doubling your payoff: winning pain relief engages endogenous pain inhibition [PDF]
, 2015 When in pain, pain relief is much sought after, particularly for individuals with chronic pain. In analogy to augmentation of the hedonic experience (“liking”) of a reward by the motivation to obtain a reward (“wanting”), the seeking of pain relief in ...
Ahmed, Alysha-Karima +4 more
core +1 more source
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Eur J Pharmacol, 173174 (2020), 2020 Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
To control or not? A motivational perspective on coping with pain [PDF]
, 2012 Pain relief is often the primordial treatment objective in pain patients. However, an exclusive focus upon pain relief may have costs. Evidence is accumulating that persistent attempts to gain control over pain may, paradoxically, hinder successful ...
Crombez, Geert +5 more
core +1 more source
Dose Effect Response of Melatonin Premedication in Oncosurgical Patients: A Randomised Controlled Trial [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Cancer patients experience higher levels of pathological anxiety than other patients. Though several studies have reported perioperative use of melatonin in alleviating preoperative anxiety with minimal side effects, research on the ...
HM Ravikiran +2 more
doaj +1 more source
Ventricular fibrillation during carotid endarterectomy and bailout stenting: a case report
JA Clinical Reports, 2022 Background Carotid artery manipulation is not a special technique but reports of intraoperative ventricular fibrillation are rare. The risk of fatal arrhythmias may be hidden behind routine surgical techniques and anesthetic management.
Yuji Ueda +5 more
doaj +1 more source
Does Exercise Decrease Pain via Conditioned Pain Modulation in Adolescents? [PDF]
, 2016 Purpose: Pain relief after exercise, exercise-induced hypoalgesia (EIH), is established across the lifespan. Conditioned pain modulation (CPM: pain inhibits pain) may be a mechanism for EIH.
Bement, Marie K. Hoeger, Stolzman, Stacy
core +2 more sources