Results 71 to 80 of about 3,287,582 (415)

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita   +7 more
wiley   +1 more source

Experimental neck muscle pain impairs standing balance in humans [PDF]

open access: yesExperimental Brain Research 192, 4 (2009) 723-9, 2009
Impaired postural control has been reported in patients with chronic neck pain of both traumatic and non-traumatic etiologies, but whether painful stimulation of neck muscle per se can affect balance control during quiet standing in humans remains unclear.
arxiv   +1 more source

Hypnotic relaxation results in elevated thresholds of sensory detection but not of pain detection [PDF]

open access: yes, 2014
Background: Many studies show an effectiveness of hypnotic analgesia. It has been discussed whether the analgesic effect is mainly caused by the relaxation that is concomitant to hypnosis.
Irnich, Dominik   +4 more
core   +1 more source

Preemptive Nalbuphine Attenuates Remifentanil-Induced Postoperative Hyperalgesia After Laparoscopic Cholecystectomy: A Prospective Randomized Double-Blind Clinical Trial

open access: yesJournal of Pain Research, 2020
Jun Hu,1,2 Shuangshuang Chen,3 Mudan Zhu,3 Yun Wu,1,2 Ping Wang,3 Jinbao Chen,3 Ye Zhang1,2 1Department of Anesthesiology, The Second Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Key Laboratory of Anesthesiology and ...
Hu J   +6 more
doaj  

Pathogenetic role of the pain threshold Hypothetical therapeutic perspectives based on the use of drugs to elevate it

open access: yesPathos, 2023
The pain threshold determines the extent of pain perception, and in some cases, its manifestation. Therefore, it is important in certain situations to increase the pain threshold. Measuring the pain threshold is challenging due to its approximate nature.
Guido Orlandini
doaj  

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier   +8 more
wiley   +1 more source

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik   +5 more
wiley   +1 more source

Low threshold unmyelinated mechanoafferents can modulate pain

open access: yesBMC Neurology, 2017
BackgroundHuman, hairy skin contains a subgroup of C-fibers, the C-low threshold mechanoreceptive afferents ((C-LTMR) C-tactile or C-touch (CT) fibers) that are linked with the signaling of affective aspects of human touch.
K. Habig   +8 more
semanticscholar   +1 more source

Perception threshold and electrode position for spinal cord stimulation [PDF]

open access: yes, 1994
The perception threshold for epidural spinal cord stimulation in chronic pain management was analyzed on 3923 testing data obtained from 136 implanted patients.
Barolat, Giancarlo   +3 more
core   +3 more sources

The Effect of Acute Physical Fatigue on Information Processing, Pain Threshold and Muscular Performance

open access: yesApplied Sciences
This study explores the multifaceted effects of acute physical fatigue on information processing, pain threshold, and muscular performance. Enrolling 28 recreational athletes, we used a high-intensity interval training (HIIT) protocol to induce fatigue ...
Vicente Javier Clemente-Suárez   +4 more
doaj   +1 more source

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