American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg +9 more
wiley +1 more source
Chronic Pain and Pain Tolerance in Psoriasis: A Cross-sectional Study of Three Population-based Cohorts in the Netherlands and Norway. [PDF]
Acta Derm VenereolBollemeijer J +12 more
europepmc +1 more source
Pain, Culture and Pedagogy: A Preliminary Investigation of Attitudes Towards "Reasonable" Pain Tolerance in the Grassroots Reproduction of a Culture of Risk. [PDF]
Psychol Rep, 2022 Miller PK, Van Der Zee S, Elliott D.
europepmc +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta +9 more
wiley +1 more source
"A pain that ruins mountains" : a case study of factors influencing postoperative pain management in two Jordanian hospitals [PDF]
Postoperative pain is still poorly managed among surgical patients despite evidence-based approaches to its treatment being well established. Prompted by the persistence of this problem, many researchers have studied factors influencing postoperative ...
Daibes, Mayada
core
Nothing to See Here: Researching Non‐Recent Child Abuse in Schools and the Politics of Silence
Australian Journal of Social Issues, EarlyView.ABSTRACT While institutions, including schools, have responsibilities to protect children from harm, responses to instances of child sexual abuse have often exhibited avoidance and denial. Recent public inquiries in Australia revealed that some institutions, particularly in the Catholic sector, employed a deliberate strategy of silence which was used ...
John Crowley +2 more
wiley +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana +5 more
wiley +1 more source
Effects of Preferred Music on Pain Tolerance During an Experimental Cold Pressor Test: A Pilot Study. [PDF]
CureusFrancisco H +2 more
europepmc +1 more source
Equine models in translational medicine: A comparative approach to human health
Animal Models and Experimental Medicine, EarlyView.This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh +1 more
wiley +1 more source
Effects of Aging on Pain Tolerance: A Comparative Study of Heat Pain Thresholds and Tonic Heat and Cold Stimuli. [PDF]
Eur J PainDevanne J, Trocmet L.
europepmc +1 more source