Results 101 to 110 of about 363,421 (298)

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

open access: yesAdvanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller   +9 more
wiley   +1 more source

KARL LYUDVIGOVICH MYUPHKE (1868–1933) – ARCHITECT-PAINTER AND CONSTRUCTOR OF SARATOV UNIVERSITY [PDF]

open access: yesСаратовский научно-медицинский журнал, 2007
Karl Lyudvigovich Myuphke (1868-1933) - architect-painter and constructor of Saratov medical university educational blocks and clinical center buildings.
Gkybochko P.V., Stepanov S.A.
doaj  

Global Expansion of National Securities Laws: Extraterritoriality and Jurisdictional Conflicts [PDF]

open access: yes, 2014
[Excerpt] “As securities fraud has grown increasingly transnational, it has become necessary to expand the reach of anti-fraud provisions to persons and entities participating in global securities markets.
Park, Junsun
core   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Single‐Particle Mid‐Infrared Photothermal Imaging Reveals Hidden Heterogeneity in Real‐World Micro‐ and Nanoplastics

open access: yesAdvanced Science, EarlyView.
Mid‐infrared photothermal imaging enables multidimensional profiling of micro‐ and nanoplastics in bottled water. A total of 9.9 × 104 particles L−1 is detected, with 64% in the nanoscale regime. Spectral evolution, including peak narrowing and band shifts, reveals local chain reorganization in polyethylene terephthalate (PET), highlighting intrinsic ...
Xinyu Deng   +4 more
wiley   +1 more source

Målaren som konstnär och allegori. Självbild, dräkt och frusen tid vid 1500-talets början

open access: yesICO Iconographisk Post, 2016
Title in English: The Painter as an Artist and Allegory. Portrait, Fashion and Frozen Time in the Early 16th Century. – Throughout the Middle Ages, self-portraits were created by the artisans who constructed and decorated churches and secular ...
Pia Bengtsson Melin
doaj  

Quantifying Strain and Its Effect on Charge Transport in Ge/Si Core/Shell Nanowires

open access: yesAdvanced Science, EarlyView.
This work demonstrates strain engineering in Ge/Si core–shell nanowires (CS NWs) by tuning the Ge core‐Si shell dimensions. Polarization‐resolved µ‐Raman and geometrical phase analysis quantify the resulting strain. Electronic transport measurements demonstrate record hole mobilities up to 25 400 cm2/Vs, highlighting these Ge/Si CS NWs as a promising ...
Aswathi K. Sivan   +14 more
wiley   +1 more source

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

open access: yesAdvanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu   +12 more
wiley   +1 more source

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