Results 151 to 160 of about 731,845 (263)
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
The Role of Entrepreneurial Strategies in Overcoming Economic Challenges in Regional Markets
Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-BiałejThis research examines the role of entrepreneurial strategies in overcoming economic challenges across ten countries: the USA, Kazakhstan, UK, India, China, Poland, Brazil, Kenya, Saudi Arabia, and Turkey, during the period 2019–2023.
Andrey Chshelokovskiy
doaj +1 more source
FolkTalent: Enhancing Classification and Tagging of Indian Folk Paintings [PDF]
arXivIndian folk paintings have a rich mosaic of symbols, colors, textures, and stories making them an invaluable repository of cultural legacy. The paper presents a novel approach to classifying these paintings into distinct art forms and tagging them with their unique salient features.
arxiv
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Everything In Its Right Place: Foucault And The 'Ideology Of The Aesthetic’ [PDF]
, 2004 There are several ways in which we 'rediscover' things. Sometimes rediscovering means finding something we had thought lost—to take a relevant example, let's say a painting that was stolen, or thought destroyed, that turns up in a dingy attic, from where
Paterson, Dominic
core +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
The opinion of St. Theophan, the Recluse, on Belokrinitskaya and Coreligionists Hierarchy
Studia Humanitatis, 2017 The article analyses the views of St. Theophan, the Recluse (1815-1894), the famous theologian and spiritual writer of the 19th century, on the Belokrinitskaya Hierarchy, which stemmed in 1846 from the Metropolitan Ambrose (Georgiopoli). St.
Kashirina Varvara Viktorovna
doaj
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source