Direct Quantification of Protein-Protein Interactions in Living Bacterial Cells. [PDF]
Yi S+12 more
europepmc +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte+23 more
wiley +1 more source
Construction of a genome-engineered stable 5-aminolevulinic acid producing <i>Corynebacterium glutamicum</i> by increasing succinyl-CoA supply. [PDF]
Zheng Y+5 more
europepmc +1 more source
Precision‐Optimised Post‐Stroke Prognoses
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope+4 more
wiley +1 more source
Pair Natural Orbitals for Coupled Cluster Quadratic Response Theory. [PDF]
Madriaga JP, Kodrycka M, Crawford TD.
europepmc +1 more source
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas+24 more
wiley +1 more source
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte+13 more
wiley +1 more source
Growth, development, and life history of a mass-reared edible insect, Gryllodes sigillatus (Orthoptera: Gryllidae). [PDF]
Kong JD+4 more
europepmc +1 more source
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone+19 more
wiley +1 more source
Engineering <i>Escherichia coli</i> for Anaerobic Succinate Fermentation Using Corn Stover Hydrolysate as a Substrate. [PDF]
Yang H, Dong Y.
europepmc +1 more source