Results 141 to 150 of about 7,975,657 (382)

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Dynamic programming re-ranking for PPI interactor and pair extraction in full-text articles

open access: yesBMC Bioinformatics, 2011
Background Experimentally verified protein-protein interactions (PPIs) cannot be easily retrieved by researchers unless they are stored in PPI databases. The curation of such databases can be facilitated by employing text-mining systems to identify genes
Lai Po-Ting, Tsai Richard
doaj   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Concepts and their Use for Modelling Objects and References in Programming Languages

open access: yes, 2007
In the paper a new programming construct, called concept, is introduced. Concept is pair of two classes: a reference class and an object class. Instances of the reference classes are passed-by-value and are intended to represent objects. Instances of the
Savinov, Alexandr
core   +1 more source

THE TRUE COST OF PAIR PROGRAMMING: DEVELOPMENT OF A COMPREHENSIVE MODEL AND TEST [PDF]

open access: yes, 2011
To advance the nomological net and theory, this dissertation proposed a comprehensive pair programming research model where the relationships among system complexity, programming methods, pair composition, effort, duration, defect rate, knowledge ...
Sun, Wenying
core  

The Effects of a Maternal Preparation Program on Mother–Infant Pairs: A Pilot Study [PDF]

open access: bronze, 1989
Carol Hamilton-Dodd   +4 more
openalex   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Suggestion and Upgrading Extreme Programming Methodology in Web-Based Project Development

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
In this research, we will discuss how to improve the work by dealing with the factors that participates in enhancing small IT organization to produce the software using the suitable development process supported by experimental theories to achieve the
A.Y. Gheni
doaj  

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