Results 131 to 140 of about 832,547 (326)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Self-consistent pairing interaction and collective motion in nuclei: a semiclassical approach

open access: yesEPJ Web of Conferences, 2012
The solutions of the semiclassical time–dependent Hartree–Fock-Bogoliubov equations of motion are studied in a linear approximation in which the pairing field is allowed to oscillate and to become complex.
Brink D.M.   +3 more
doaj   +1 more source

On the pairing of polarizations

open access: yesCommunications in Mathematical Physics, 1978
IfF is a positive Lagrangian sub-bundle of a symplectic vector bundle (E, ω) we show by elementary means that the Chern classes ofF are determined by ω. The notions of metaplectic structure for (E, ω), metalinear structure forF and square root ofKF, the canonical bundle ofF are shown to be essentially the same.
openaire   +4 more sources

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Matching Final Year Project Topics with Students using Stable Marriage Model

open access: yesJournal of Computing Research and Innovation, 2018
Every semester, a new batch of final year students needs to find a topic and a supervisor to complete their final year project requirement. The problem with the current approach is that it is based on first come first serve.
Naimah Mohd Hussin, Ammar Azlan
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

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