Results 181 to 190 of about 663,412 (296)

Exploring Secondary Structure Predictions for RNA-Targeted Drug Discovery: Power and Challenges. [PDF]

J Chem Inf Model
Zhang Z, Dolcetti G, Tyrchan C, De Maria L, Bussi G, Czechtizky W.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

RIMap-RISC: a transcriptome-wide database of structurally modeled human microRNA interactions. [PDF]

Genome Biol
Chasles S, Gaillard-Duchassin Z, Quenneville J, Lemaire M, Gagnon E, Major F.   +5 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation. [PDF]

Nature
Farnung J, Slobodyanyuk E, Wang PY, Blodgett LW, Lin DH, von Gronau S, Schulman BA, Bartel DP.   +7 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Beyond Interfacial Structure: Ion Transport Mediates Cation Effects in Electrochemical Nitrate Reduction. [PDF]

ACS Electrochem
Murphy MA, Fong KD.
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Editorial: Molecular architecture and dynamics of meiotic chromosomes

Frontiers in Cell and Developmental Biology
Ricardo Benavente, Ricardo Benavente, Mónica Pradillo, Pedro A. San-Segundo   +3 more
doaj   +1 more source

Specific ion effects on ion transport in charged polymer membranes. [PDF]

Sci Adv
Kitto D, Reimonn G, Vickers R, Espinoza C, Silverman AG, Goldsmith BR, Kamcev J.   +6 more
europepmc   +1 more source