Results 71 to 80 of about 198,228 (265)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nilpotent Pairs, Dual Pairs, and Sheets

open access: yesJournal of Algebra, 2001
Recently, V.Ginzburg introduced the notion of a principal nilpotent pair (= pn-pair) in a semisimple Lie algebra {\frak g}. It is a double counterpart of the notion of a regular nilpotent element. A pair (e_1,e_2) of commuting nilpotent elements is called a pn-pair, if the dimension of their simultaneous centralizer is equal to the rank of {\frak g ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Proton–neutron pairing in N=Z nuclei: Quartetting versus pair condensation

open access: yesPhysics Letters B, 2015
The isoscalar proton–neutron pairing and isovector pairing, including both isovector proton–neutron pairing and like-particle pairing, are treated in a formalism which conserves exactly the particle number and the isospin.
N. Sandulescu, D. Negrea, D. Gambacurta
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The monodromy pairing [PDF]

open access: yesAsian Journal of Mathematics, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Self-pairings on hyperelliptic curves

open access: yesJournal of Mathematical Cryptology, 2013
A self-pairing is a pairing computation where both inputs are the same group element. Self-pairings are used in some cryptographic schemes and protocols. In this paper, we show how to compute the Tate–Lichtenbaum pairing on a curve more efficiently than
Galbraith Steven D., Zhao Chang-An
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Symmetry restoration in the mean-field description of proton-neutron pairing

open access: yesPhysics Letters B, 2019
We show that the symmetry-restored paired mean-field states (quasiparticle vacua) properly account for isoscalar versus isovector nuclear pairing properties. Full particle-number, spin, and isospin symmetries are restored in a simple SO(8) proton-neutron
A.M. Romero, J. Dobaczewski, A. Pastore
doaj   +1 more source

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