Severe Restriction of Glucose Import Enhances Recombinant Protein Production in Escherichia coli. [PDF]
Graphical Abstract and Lay Summary Producing recombinant proteins in Escherichia coli is often limited by the bacterium's tendency to consume glucose too rapidly. This excessive glucose uptake causes overflow metabolism, leading to the accumulation of acetate, a byproduct that can reduce cellular performance and protein production.
Fragoso-Jiménez JC +5 more
europepmc +2 more sources
Generating Dynamic Structures Through Physics-Based Sampling of Predicted Inter-Residue Geometries. [PDF]
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Xiang C, Wang W, Peng Z, Yang J.
europepmc +2 more sources
Transforming Care in Cystic Fibrosis: The Long-Term Impact of Quality Improvement Projects on Clinical Outcomes. [PDF]
ABSTRACT Objective This study aimed to evaluate 5‐year outcomes of a structured quality improvement (QI) program implemented as part of the standard of care at our CF center, focusing on changes in body mass index (BMI) and forced expiratory volume in 1 s (FEV₁) in pwCF followed at our institution.
Karabulut S +14 more
europepmc +2 more sources
Upper Bounds on the BER Performance of MTCM-STBC Schemes over Shadowed Rician Fading Channels
Space-time block coding (STBC) provides substantial diversity advantages with a low decoding complexity. However, these codes are not designed to achieve coding gains. Outer codes should be concatenated with STBC to provide additional coding gain.
M. Uysal, C. N. Georghiades
doaj +1 more source
Neural Dynamics of Social Cognition: A Single-Trial Computational Analysis of Learning Under Uncertainty. [PDF]
We apply a hierarchical Bayesian model to single‐trial EEG data from an advice‐taking task, demonstrating that EEG activity closely mirrors the predicted sequence of prediction errors and precision signals. Additionally, source‐localised activity in the fusiform gyrus and posterior cingulate cortex covaried with participants' psychosocial functioning ...
Charlton CE +8 more
europepmc +2 more sources
Distributed Space-Time Block Code over Mixed Rayleigh and Rician Frequency-Selective Fading Channels
This paper proposes a new distributed space-time block code (DSTBC) over frequency-selective fading channels for two-hop amplify and forward relay networks, consisting of a source node (S), two relay nodes (R1 and R2), and a destination node (D).
Quoc-Tuan Vien +2 more
doaj +2 more sources
In wireless two-way (TW) relay channels, denoise-and-forward (DNF) network coding (NC) is a promising technique to achieve spectral efficiency. However, unsuccessful detection at relay severely deteriorates the diversity gain, as well as end-to-end ...
Yulun Cheng, Longxiang Yang
doaj +1 more source
Polar Codes With Repeating Bits and the Construction by Cluster Pairwise Error Probability
A polar code with repeating bits (RB polar code), where a part of frozen bits only repeat their preceding information bits, is proposed. In the code construction, we propose cluster pairwise error probability (CPEP) to measure the competitiveness of the ...
Tao Wang, Daiming Qu, Tao Jiang
doaj +1 more source
As a low-complexity and energy-efficient multiple input multiple output (MIMO) technique, spatial modulation (SM) has received much interest recently.
Xiangbin Yu +4 more
doaj +1 more source
New Design of Constellation and Bit Mapping for Dual Mode OFDM-IM
Dual mode orthogonal frequency division multiplexing with index modulation (DM-OFDM-IM) is recently proposed, where the subcarriers within each subblock are divided into two groups, which are modulated by two distinguishable signal constellations.
Kee-Hoon Kim, Hosung Park
doaj +1 more source

