Results 41 to 50 of about 917 (168)

Shared and specific molecular mechanisms of proteasome inhibitors in chemotherapy‐induced peripheral neurotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon   +27 more
wiley   +1 more source

Nurturing Futures: Foster Carer Perspectives on Looking After Unaccompanied Asylum‐Seeking Children With Histories of Trafficking

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT This article presents the findings of a small‐scale qualitative study exploring the experiences of Foster Carers looking after unaccompanied asylum‐seeking children (UASC) who are identified or suspected victims of child trafficking (‘UASTC’—unaccompanied asylum‐seeking and trafficked children).
Rosie Galbraith
wiley   +1 more source

Equity considerations in the proposed wildlife protocol to the Convention against Transnational Organized Crime

open access: yesConservation Biology, EarlyView.
ABSTRACT Wildlife trafficking poses a critical threat to global biodiversity, contributes to organized crime, and has disproportionate impacts on underserved and Indigenous communities. Although international legal instruments, such as the Convention on International Trade in Endangered Species of Wild Fauna and Flora, and institutional collaborations,
Chad Patrick Osorio
wiley   +1 more source

Unveiling Rare Genetic Variants in DAB2IP: New Insights Into the Pathogenesis of Recurrent Angioedema

open access: yes
Allergy, EarlyView.
Maurizio Margaglione   +8 more
wiley   +1 more source

Reconsidering the role of introduced species in the climate‐affected and highly invaded eastern Mediterranean

open access: yesConservation Biology, EarlyView.
Abstract Bioinvasions are considered mostly as a biodiversity and conservation hazard, but in specific situations, introduced species can bring ecological or socioeconomic benefits. We assessed the social–ecological role of marine introduced species in the eastern Mediterranean Sea—a global hotspot of bioinvasions and extirpations—and their potential ...
Stelios Katsanevakis   +7 more
wiley   +1 more source

Scientists’ warning on the global destruction of rock outcrop ecosystems

open access: yesConservation Biology, EarlyView.
Abstract Rock outcrops are geological formations that harbor a highly specialized biota adapted to harsh environmental conditions that differ from their surrounding landscapes. They are globally distributed, especially in old, highly weathered landscapes, and can function as habitat islands containing high levels of endemism and distinct evolutionary ...
Luiza F. A. de Paula   +19 more
wiley   +1 more source

Regional Standardization of CLL Management: Results of a Delphi Consensus Process

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino   +22 more
wiley   +1 more source

Cholestatic Hepatitis in Young Migrants Exposed to Fuel Vapours: An Emerging Toxicity From the Mediterranean Sea

open access: yes
Acta Paediatrica, EarlyView.
Antonio Corsello   +4 more
wiley   +1 more source

Why do defensive routines persist in organizational contexts? Results from a two‐year ethnographic action research

open access: yesEuropean Management Review, EarlyView.
Abstract Literature offers valuable insight into defensive routines, which are acknowledged by academics as barriers to organizational learning and innovation. Nevertheless, we find that there is a lack of attention in examining why defensive routines are persistent in organizational life.
Mercedes‐Victoria Auqui‐Caceres   +1 more
wiley   +1 more source

Risk Disclosure as a Resilience Tool in Central Governments: Assessing Current Practices in the United Kingdom and the Netherlands

open access: yesFinancial Accountability &Management, EarlyView.
ABSTRACT To be resilient, governments must quickly adapt their policies and working methods to new and uncertain situations. This article examines whether risk disclosure, as part of the anticipatory capacities of these organizations, can help identify and mitigate vulnerabilities.
Ekaterina Svetlova   +2 more
wiley   +1 more source

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