Results 231 to 240 of about 22,958 (312)

Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single‐center retrospective cohort study

open access: yesAndrology, EarlyView.
Abstract Background Current advances in high‐throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.
Linlin Li   +4 more
wiley   +1 more source

Structural Prediction of Coronavirus s2m Kissing Complexes and Extended Duplexes. [PDF]

open access: yesACS Phys Chem Au
Kensinger AH   +3 more
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

A Novel Parvovirus Associated with the Whitefly <i>Bemisia tabaci</i>. [PDF]

open access: yesPathogens
Gousi F   +4 more
europepmc   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends. [PDF]

open access: yesNat Commun
Hickman AB   +13 more
europepmc   +1 more source

Long Palindromic Sequences Induce Double-Strand Breaks during Meiosis in Yeast

open access: green, 2000
Farooq Nasar   +2 more
openalex   +1 more source

Status quo and future developments in the diagnosis and treatment of hereditary angioedema

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley   +1 more source

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei   +8 more
wiley   +1 more source

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