Causal Effect of Dietary Patterns on Cerebral Small Vessel Disease: A Mendelian Randomization Study
This Mendelian randomization (MR) study reveals causal links between dietary factors and cerebral small vessel disease (CSVD) neuroimaging markers. Genetically predicted higher polyunsaturated fatty acid (PUFA) levels reduce white matter hyperintensity volume, while monounsaturated fatty acid (MUFA) intake lowers lobar brain microbleeds (BMB) risk.
Yong Zeng +5 more
wiley +1 more source
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
A Novel Parvovirus Associated with the Whitefly <i>Bemisia tabaci</i>. [PDF]
Gousi F +4 more
europepmc +1 more source
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala +10 more
wiley +1 more source
fastp 1.0: An ultra-fast all-round tool for FASTQ data quality control and preprocessing. [PDF]
Chen S.
europepmc +1 more source
On Chomsky Hierarchy of Palindromic Languages (Algebraic Systems and Theoretical Computer Science)
Pál Dömösi +2 more
openalex +1 more source
ABSTRACT Background Gestational diabetes mellitus (GDM), a common pregnancy complication characterized by maternal hyperglycemia, negatively impacts offspring health. Skeletal muscle, a critical tissue for glucose and lipid metabolism, is especially vulnerable to prenatal environmental insults.
Rui Liu +7 more
wiley +1 more source
High hydrostatic pressure promotes gene transcription via a cystathionine-β-synthase domain-containing protein in the hyperthermophilic archaeon Pyrococcus yayanosii. [PDF]
Li C, Li S, Song Q, Da LT, Xu J.
europepmc +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis. [PDF]
Friedenson B.
europepmc +1 more source

