Results 41 to 50 of about 30,176 (325)

Characterization of the integration and modular excision of the integrative conjugative element PAISt in Streptomyces turgidiscabies Car8. [PDF]

open access: yesPLoS ONE, 2014
PAISt is a large genomic island located in the chromosome of the plant pathogen Streptomyces turgidiscabies Car8. The island carries clustered virulence genes, transfers to other Streptomyces species, and integrates by site-specific recombination at the ...
Jose C Huguet-Tapia   +2 more
doaj   +1 more source

Growth Inhibitory Efficacy of Chinese Herbs in a Cellular Model for Triple-Negative Breast Cancer

open access: yesPharmaceuticals, 2021
Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor-α progesterone receptor and human epidermal growth factor receptor-2.
Nitin T. Telang   +2 more
doaj   +1 more source

Species-specific Typing of DNA Based on Palindrome Frequency Patterns

open access: yesDNA Research, 2011
DNA in its natural, double-stranded form may contain palindromes, sequences which read the same from either side because they are identical to their reverse complement on the sister strand.
Estelle Lamprea-Burgunder   +2 more
semanticscholar   +1 more source

Poetic Dialogue from the Periphery of World Literature: Goethe’s Faust and the Korean Novel Kumo-shinwha

open access: yesInterlitteraria, 2018
A short but cardinal passage of Goethe’s Faust is the rhymed dialogue between Faust and Helen at their first encounter: the depiction of the very idealistic encounter consists of the process by which the ancient Greek mythical figure Helen learns about ...
Young-Ae Chon
doaj   +1 more source

The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease

open access: yesNucleic Acids Research, 2012
Extragenic sequences in genomes, such as microRNA and CRISPR, are vital players in the cell. Repetitive extragenic palindromic sequences (REPs) are a class of extragenic sequences, which form nucleotide stem-loop structures.
S. Messing   +7 more
semanticscholar   +1 more source

Inner Palindromic Closure

open access: yesInternational Journal of Foundations of Computer Science, 2013
We introduce the inner palindromic closure as a new operation ♠, which consists in expanding a factor u to the left or right by a non-empty word v such that vu or uv, respectively, is a palindrome of minimal length. We investigate several language theoretic properties of the iterated inner palindromic closure ♠*(w) = Ui≥0 ♠i(w) of a word w.
DASSOW, JÜRGEN   +3 more
openaire   +2 more sources

Improved vectors and genome-wide libraries for CRISPR screening

open access: yesNature Methods, 2014
Genome-wide, targeted loss-of-function pooled screens using the CRISPR (clustered regularly interspaced short palindrome repeats)–associated nuclease Cas9 in human and mouse cells provide an alternative screening system to RNA interference (RNAi) and ...
Neville E. Sanjana   +2 more
semanticscholar   +1 more source

FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity

open access: yesNature Communications, 2022
Gene editing tools have tremendous potential for biomedical and basic research. Here the authors report a Cas9 from Faecalibaculum rodentium (FrCas9) that achieves efficient and specific gene editing in human cells with a NNTA palindrome PAMs for ...
Zifeng Cui   +14 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Influencia de la orientación de la luz arterial del catéter venoso central tunelizado para hemodiálisis en la disfunción precoz

open access: yesEnfermería Nefrológica, 2022
Introducción: La disfunción y las infecciones son las causas más frecuentes de retirada de los catéteres venosos centrales tunelizados para hemodiálisis.
Juan Manuel Manzano Angua   +4 more
doaj   +1 more source

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