Results 61 to 70 of about 30,176 (325)

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Position and sequence conservation in Amniota of polymorphic enhancer HS1.2 within the palindrome of IgH 3'Regulatory Region

BMC Evolutionary Biology, 2011
BackgroundThe Immunoglobulin heavy chain (IgH) 3' Regulatory Region (3'RR), located at the 3' of the constant alpha gene, plays a crucial role in immunoglobulin production.
P. D'addabbo, M. Scascitelli, V. Giambra, M. Rocchi, D. Frezza   +4 more
semanticscholar   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Over/exposure in The Atlas by William T. Vollmann

Sillages Critiques, 2013
This paper examines the way Vollmann uses photography and text in a palindrome composition in The Atlas, among other figures of symmetry, to frame the other as oneself.
Françoise Palleau-Papin
doaj   +1 more source

Genetic diversity of Escherichia coli isolated from commercial swine farms revealed by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) and repetitive extragenic palindrome PCR (REP-PCR)

, 2011
The objective of this study was to use enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) and repetitive extragenic palindrome PCR (REP-PCR) for the analysis of genetic diversity among Escherichia coli strains isolated from commercial swine ...
L. Wan, Zhi-Biao Wang, Q. Yan, Xu Wang, Y. Lei, Lan Zuo, Yu Cheng, Yupeng Ren, Wan-zhu Guo   +8 more
semanticscholar   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Identification of the regulatory logic controlling Salmonella pathoadaptation by the SsrA-SsrB two-component system. [PDF]

PLoS Genetics, 2010
Sequence data from the past decade has laid bare the significance of horizontal gene transfer in creating genetic diversity in the bacterial world. Regulatory evolution, in which non-coding DNA is mutated to create new regulatory nodes, also contributes ...
Ana M Tomljenovic-Berube, David T Mulder, Matthew D Whiteside, Fiona S L Brinkman, Brian K Coombes   +4 more
doaj   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

Grupos de nudos con dos generadores

Revista Integración, 2011
Se estudian grupos de nudos que admiten una presentación con dos generadores y una relación. Decimos que una presentación a, b | r es palindrómica si r es una palabra palíndromo, es decir, r es una palabra que se lee lo mismo de adelante para atrás ...
Christian Pommerenke, Margarita Toro
doaj  

Calibration of weather radars with a target simulator [PDF]

Atmospheric Measurement Techniques
We present findings from radar calibration experiments involving three radars operated by the Colorado State University (CSU) in the US and by the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland.
M. Schneebeli, M. Schneebeli, A. Leuenberger, P. J. Schmid, P. J. Schmid, J. Grazioli, H. Corden, A. Berne, P. Kennedy, J. George, F. Junyent, V. Chandrasekar   +11 more
doaj   +1 more source