Results 61 to 70 of about 11,659 (270)

Grupos de nudos con dos generadores

Revista Integración, 2011
Se estudian grupos de nudos que admiten una presentación con dos generadores y una relación. Decimos que una presentación a, b | r es palindrómica si r es una palabra palíndromo, es decir, r es una palabra que se lee lo mismo de adelante para atrás ...
Christian Pommerenke, Margarita Toro
doaj  

Deciphering the importance of the palindromic architecture of the immunoglobulin heavy-chain 3’ regulatory region

Nature Communications, 2016
The IgH3’ regulatory region contains an evolutionarily conserved palindromic sequence flanking important enhancer elements. Here the authors show that the palindrome is required for generating antibody diversity.
Alexis Saintamand, Christelle Vincent-Fabert, Armand Garot, Pauline Rouaud, Zeliha Oruc, Virginie Magnone, Michel Cogné, Yves Denizot   +7 more
doaj   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Enhanced the Trans‐Cleavage Activity of CRISPR‐Cas12a Using Metal‐Organic Frameworks as Stimulants for Efficient Electrochemical Sensing of Circulating Tumor DNA

Advanced Science, EarlyView.
This work designs manganese metal‐organic frameworks (Mn‐MOFs) co‐assembled with Cas12a/crRNA, enabling rapid release of Mn2⁺ under mild conditions. The MOFs‐induced proximity effect sustains Mn2⁺‐Cas12a/crRNA interactions, enhancing the trans‐cleavage activity of complex available to develop an electrochemical biosensor based on Mn‐MOFs‐enhanced ...
Shuai Wu, Yincheng Liu, Tianyu Zeng, Tianci Zhou, Yanting Sun, Ying Deng, Juan Zhang, Genxi Li, Yongmei Yin   +8 more
wiley   +1 more source

Folate Receptor‐Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells

Small, Volume 19, Issue 2, January 11, 2023., 2023
For therapeutic genome editing, efficient and cell‐specific transport of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated protein 9 (Cas9) system into target cells is desirable. Here, folic acid‐modified Cas9 ribonucleoprotein nanocarriers are presented, which mediate enhanced gene modification in folate receptor
Yi Lin, Ulrich Wilk, Jana Pöhmerer, Elisa Hörterer, Miriam Höhn, Xianjin Luo, Hongcheng Mai, Ernst Wagner, Ulrich Lächelt   +8 more
wiley   +1 more source

Counting scattered palindromes in a finite word [PDF]

arXiv, 2021
We investigate the scattered palindromic subwords in a finite word. We start by characterizing the words with the least number of scattered palindromic subwords. Then, we give an upper bound for the total number of palindromic subwords in a word of length $n$ in terms of Fibonacci number $F_n$ by proving that at most $F_n$ new scattered palindromic ...
arxiv  

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Variasi Bahasa Kaum Milenial: Bentuk Akronim dan Palindrom dalam Media Sosial

Estetik, 2020
Modernity makes language develop quickly, one of which is the emergence of new vocabularies of Indonesian language. The meanings of vocabularies that emerge are often not understood, thus making the communication process not conveyed.
Syihaabul Hudaa, Ahmad Bahtiar
doaj   +1 more source

Properties of palindromes in finite words [PDF]

Pure Math. Appl. 17, 3-4 (2006) pp. 183-195, 2010
We present a method which displays all palindromes of a given length from De Bruijn words of a certain order, and also a recursive one which constructs all palindromes of length $n+1$ from the set of palindromes of length $n$. We show that the palindrome complexity function, which counts the number of palindromes of each length contained in a given ...
arxiv  

The MdHB7L–MdICE1L–MdHOS1 Module Fine‐Tunes Apple Cold Response via CBF‐Dependent and CBF‐Independent Pathways

Advanced Science, EarlyView.
In early cold response, MdICE1L utilizes MdHB7L as a cofactor to facilitate the transcriptional activation of MdCBFs, thereby activating cold signaling rapidly and strongly. Subsequently, MdICE1L is degraded by MdHOS1. Meanwhile, MdHB7L is released and accumulates.
Jie Yang, Na Li, Ming Li, Ran Yi, Lina Qiu, Kangning Wang, Shuang Zhao, Fengwang Ma, Ke Mao   +8 more
wiley   +1 more source