Perfect palindromic lac operator DNA sequence exists as a stable cruciform structure in supercoiled DNA in vitro but not in vivo. [PDF]
, 1983 Richard R. Sinden +2 more
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Small Structures, EarlyView.Cas12Fold, a deep‐learning framework tailored to Cas12 nucleases, uses evolutionary signals and iterative structure‐based alignment to resolve conformational complexity. This method outperforms general models in predicting key domains and states, accurately modeling enzymes such as Casλ.
Feng Xu +12 more
wiley +1 more source
CRISPR typing and phage content of colonizing Group B Streptococci from healthy Egyptian women
Frontiers in Cellular and Infection MicrobiologyBackgroundStreptococcus agalactiae or Group B Streptococcus (GBS) causes serious infections in neonates with a particularly high burden of disease in Africa. Maternal vaginal colonization is the primary source of neonatal transmission.
Sarah Shabayek +9 more
doaj +1 more source
Insect Science, EarlyView.The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi +3 more
wiley +1 more source
Runs, Squares, Palindromes, and Unbordered Factors of a Family of Binary Pattern Sequences with the All-One Pattern [PDF]
Russell Jay Hendel
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The transformer gene controls sexual development in Drosophila suzukii
Insect Science, EarlyView.The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan +8 more
wiley +1 more source
Genetic engineering for SIT application: a fruit fly‐focused review
Insect Science, EarlyView.Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova +2 more
wiley +1 more source
Molecular mechanisms of sex determination in Lepidoptera: current status and perspectives
Insect Science, EarlyView.The genetic basis of sex determination in Lepidoptera was discovered in 2014 in the silkworm Bombyx mori. In this model species, the W chromosome‐derived small piRNA called Fem piRNA downregulates the expression of a Z‐linked gene, Masculinizer (Masc), which leads to the default female‐specific splicing of the doublesex gene (dsxF) and thus to female ...
František Marec +2 more
wiley +1 more source
Quasi-palindromic sequences: a model for template-switch mutagenesis avoidance and stimulation
, 2015 Stephen Gross
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Unique sequence arrangement of ribosomal genes in the palindromic rDNA molecule of Physarum polycephalum [PDF]
, 1979 Gerald R. Campbell +4 more
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