Results 151 to 160 of about 2,912,653 (308)

On the Classification of Universal Rotor-Routers [PDF]

open access: yes, 2011
The combinatorial theory of rotor-routers has connections with problems of statistical mechanics, graph theory, chaos theory, and computer science. A rotor-router network defines a deterministic walk on a digraph G in which a particle walks from a source
He, Xiaoyu
core  

Light‐Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression

open access: yesAngewandte Chemie International Edition, Accepted Article.
A photo‐triggered CRISPR/Cas12a machinery for in vitro and in vivo gene editing is introduced. The system consists of a caged, inactive ortho‐nitrobenzyl phosphate ester photo‐responsive crRNA, which, upon light‐induced deprotection, yields the active CRISPR/Cas12a gene editing machinery (LAC12aGE).
Hong Liu   +7 more
wiley   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

open access: yesAnimal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah   +4 more
wiley   +1 more source

Honey Bee Breeding and Breed: Advancements, Challenges, and Prospects

open access: yesAnimal Research and One Health, EarlyView.
Our work clarifies concepts related to honey bee classification, reviews traditional and modern breeding techniques, explores advancements in molecular breeding, prospects gene‐editing tools, and advocates for integrated breeding strategies to ensure the long‐term sustainability and vitality of honey bee populations amid declining managed populations ...
Zheguang Lin   +5 more
wiley   +1 more source

Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy

open access: yesChemPlusChem, EarlyView.
Recent advances in the field of nucleic acid nuclear magnetic resonance (NMR) are presented. Stable isotope labeling protocols and new approaches to segmentally label nucleic acid with NMR‐active residues are summarized. The novel methods will have a strong impact on the future of nucleic acid NMR and the characterization of structure and dynamics of ...
Stefan Hilber   +3 more
wiley   +1 more source

Twisted conjugacy in braid groups

open access: yes, 2011
In this note we solve the twisted conjugacy problem for braid groups, i.e. we propose an algorithm which, given two braids $u,v\in B_n$ and an automorphism $\phi \in Aut (B_n)$, decides whether $v=(\phi (x))^{-1}ux$ for some $x\in B_n$.
González-Meneses, Juan, Ventura, Enric
core  

Highly Iterated Palindromic Sequences (HIPs) and Their Relationship to DNA Methyltransferases [PDF]

open access: yesLife, 2015
The sequence GCGATCGC (Highly Iterated Palindrome, HIP1) is commonly found in high frequency in cyanobacterial genomes. An important clue to its function may be the presence of two orphan DNA methyltransferases that recognize internal sequences GATC and CGATCG.
openaire   +5 more sources

Perfect palindromic lac operator DNA sequence exists as a stable cruciform structure in supercoiled DNA in vitro but not in vivo.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1983
A perfect palindromic 66-base pair (bp) DNA sequence derived from the lac operator and cloned into plasmid pMB9 [Betz, J. L. & Sadler, J. R. (1981) Gene 13, 1-12] can exist in a 66-bp linear form or as two 33-bp cruciform arms.
R. Sinden, S. Broyles, D. Pettijohn
semanticscholar   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou   +6 more
wiley   +1 more source

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