iLABMED, EarlyView.Circulating tumor cell (CTC) analysis has become a powerful tool for the early diagnosis of cancer, monitoring disease progression, and evaluating treatment efficacy. This article reviews the latest progress in CTC detection, capture, and release methods based on DNA materials and provides insights into current development trends and future research ...
Lin Zhou, Yongchang Yang, Jie Liu
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Current Progress in Targeting Human Cytomegalovirus Infection
iLABMED, EarlyView.This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
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The restriction endonuclease R.NmeDI from Neisseria meningitidis that recognizes a palindromic sequence and cuts the DNA on both sides of the recognition sequence [PDF]
, 2007 Agnieszka Kwiatek, Andrzej Piekarowicz
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iMeta, EarlyView.This study proposes an innovative therapeutic approach by combining RRM2 gene knockout with a nanocarrier system, significantly enhancing the efficacy of radiofrequency ablation for hepatocellular carcinoma. The study developed a tumor microenvironment‐responsive nanosystem that achieves synergistic effects through SPIO‐mediated and RRM2 knockout ...
Weiliang Hou +19 more
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Long Palindromic Sequences Induce Double-Strand Breaks during Meiosis in Yeast
, 2000 Farooq Nasar +2 more
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Complete mitochondrial genome sequences ofâ threeNakaseomycesspecies reveal invasion by palindromic GC clusters and considerable size expansion [PDF]
, 2009 Christiane Bouchier +4 more
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fastp 1.0: An ultra‐fast all‐round tool for FASTQ data quality control and preprocessing
iMeta, EarlyView.The figure shows side‐by‐side quality comparison of the data before and after preprocessing using fastp 1.0. As can be seen from this figure, the data quality has been significantly improved after fastp processing. The Q20 ratio and Q30 ratio increased, and the GC base ratio returned to balance.
Shifu Chen
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Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells [PDF]
, 2009 Hiroki Kurahashi +9 more
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New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
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