Results 21 to 30 of about 334,904 (302)

Dual-Bioorthogonal Catalysis by a Palladium Peptide Complex

Journal of Medicinal Chemistry, 2023
Artificial metalloenzymes (ArMs) enrich bioorthogonal chemistry with new-to-nature reactions while limiting metal deactivation and toxicity. This enables biomedical applications such as activating therapeutics in situ. However, while combination therapies are becoming widespread anticancer treatments, dual catalysis by ArMs has not yet been shown.
Ana M. Pérez-López, Adam Belsom, Linus Fiedler, Xiaoyi Xin, Juri Rappsilber   +4 more
openaire   +3 more sources

Pd-CuFe Catalyst for Transfer Hydrogenation of Nitriles: Controllable Selectivity to Primary Amines and Secondary Amines

iScience, 2018
Summary: A multicomponent nanocatalyst system was fabricated for the transfer hydrogenation of nitrile compounds. This catalyst system contains palladium, copper, and iron, which are supported on the magnetite nanospheres, and the loading of palladium ...
Lei Liu, Yuhong Liu, Yongjian Ai, Jifan Li, Junjie Zhou, Zhibo Fan, Hongjie Bao, Ruihang Jiang, Zenan Hu, Jingting Wang, Ke Jing, Yue Wang, Qionglin Liang, Hongbin Sun   +13 more
doaj   +1 more source

Monodisperse CuPd alloy nanoparticles supported on reduced graphene oxide as efficient catalyst for directed C−H activation

Catalysis Communications, 2021
The palladium-catalyzed selective activation of CH bonds is of great importance for the construction of diverse bioactive molecules. Herein, monodisperse CuPd alloy nanoparticles supported on reduced graphene oxide have been used as high efficient and ...
Feifan Wang, Fei Huang, Yingliang Yu, Shuangliu Zhou, Zhenghua Wang, Wu Zhang   +5 more
doaj   +1 more source

Non-innocent hybrid cycloolefin ligands for palladium/olefin cooperative catalysis [PDF]

, 2021
Catalyst design is a key research area in modern synthetic chemistry. Engineering of molecular catalysts in homogeneous catalysis brings about new catalytic modes that enable efficient synthetic transformations.
Ya-Xin, Zheng, Lei, Jiao
core   +2 more sources

Direct access to spirocycles by Pd/WingPhos-catalyzed enantioselective cycloaddition of 1,3-enynes

Nature Communications, 2021
Spirocycles are traditionally difficult structures to synthesize due to the congested nature of the central atom. Here the authors show a method to synthesize quaternary carbon spirocycles in one step from 1,3-enynes and pyrazolidine-type heterocycles ...
Long Li, Shan Wang, Pengfei Luo, Ran Wang, Zheng Wang, Xiaoguang Li, Yuhua Deng, Fangzhi Peng, Zhihui Shao   +8 more
doaj   +1 more source

Synergetic iridium and amine catalysis enables asymmetric [4+2] cycloadditions of vinyl aminoalcohols with carbonyls

Nature Communications, 2019
Inverse electron-demand cycloadditions in palladium catalysis are inherently limited by the linear selectivity in the allylic substitution step. To overcome this issue, the authors report a synergetic iridium (branched-selective) and amine catalysis in ...
Mao-Mao Zhang, Ya-Ni Wang, Bao-Cheng Wang, Xiao-Wang Chen, Liang-Qiu Lu, Wen-Jing Xiao   +5 more
doaj   +1 more source

SCS-pincer palladium-catalyzed auto-tandem catalysis using dendritic catalysts in semi-permeable compartments [PDF]

, 2011
Novel monometallic and dendritic SCS-pincer palladium complexes 2, 3 and 4 have been synthesized in good yields (60–89%) and high purity (palladium loading >97%).
van Koten, G., Sub Chem Biol & Organic Chem begr 1-6-12, Organic Chemistry and Catalysis, Pijnenburg, N.J.M., Dijkstra, H.P., Klein Gebbink, R.J.M., Dep Scheikunde   +6 more
core   +1 more source

Unactivated Alkyl Chloride Reactivity in Excited-State Palladium Catalysis

, 2021
Excited-state palladium catalysis is an efficient process for the alkylation of diverse organic compounds via the generation of alkyl radicals from alkyl bromides and iodides.
Gimnkhan, Aidana, Rueping, Magnus, Kancherla, Rajesh, Muralirajan, Krishnamoorthy   +3 more
core   +1 more source

Axially Chiral Cyclic Diphosphine Ligand-Enabled Palladium-Catalyzed Intramolecular Asymmetric Hydroarylation

iScience, 2018
Summary: In transition metal-catalyzed asymmetric synthesis, enantioselectivity strongly depends on the structures of chiral ligands, so the development of new chiral ligands is crucial.
Can Liu, Xianjin Zhu, Pengxiang Zhang, Haijun Yang, Changjin Zhu, Hua Fu   +5 more
doaj   +1 more source

Cationic-palladium catalyzed regio- and stereoselective syn-1,2-dicarbofunctionalization of unsymmetrical internal alkynes

Nature Communications, 2022
Methods to regioselectively difunctionalize unsymmetrical alkynes with two diverse carbon-based substituents are rare. Here the authors show a method to add two C(sp2)-based units in a syn, regioselective fashion across a triple bond, via palladium ...
Shubham Dutta, Shashank Shandilya, Shengwen Yang, Manash Protim Gogoi, Vincent Gandon, Akhila K. Sahoo   +5 more
doaj   +1 more source