Results 201 to 210 of about 241,973 (264)

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Surgical Procedure and Postoperative S-1 Chemotherapy Deliverability in Symptomatic Stage IV Gastric Cancer. [PDF]

In Vivo
Higashizono K, Watanabe M, Nagai E, Taki Y, Nishida M, Sato S, Nakatani E, Baba Y, Kanemoto H.   +8 more
europepmc   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Culturally Sensitive End-of-Life Care for Persons With Dementia: A Global Scoping Review and Conceptual Framework. [PDF]

J Transcult Nurs
Wang WG, Li C, Murali KP.
europepmc   +1 more source

Symptom and problem burden, performance status and palliative care phases in specialist palliative care: cross-sectional analysis of care episodes. [PDF]

BMJ Support Palliat Care
Lehmann-Emele E, Gesell D, Hodiamont F, Wikert J, Bausewein C.   +4 more
europepmc   +1 more source

Growing palliative and end-of-life care research in the United Kingdom: Findings from a mixed methods survey. [PDF]

PLoS One
Okamoto I, Jin A, Etkind SN, Wakefield D, McConnell T, Byrne A, Dharamshi YV, Murtagh F, Finucane A.   +8 more
europepmc   +1 more source

Decisions about palliative care and social determinants of health in intensive care units: a scoping review. [PDF]

Acute Crit Care
Yun H, Kim JY, Han E, Jang Y.
europepmc   +1 more source

Palliative psychiatry

Tidsskrift for Den norske legeforening
Carl Tollef Solberg, Anders Malkomsen
openaire   +2 more sources