Results 41 to 50 of about 45,616 (250)

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

EgJUB1 and EgERF113 transcription factors as potential master regulators of defense response in Elaeis guineensis against the hemibiotrophic Ganoderma boninense

BMC Plant Biology, 2021
Background Hemibiotrophic pathogen such as the fungal pathogen Ganoderma boninense that is destructive to oil palm, manipulates host defense mechanism by strategically switching from biotrophic to necrotrophic phase.
Nurshafika Mohd Sakeh, Siti Nor Akmar Abdullah, Mohammad Nazri Abdul Bahari, Azzreena Mohamad Azzeme, Noor Azmi Shaharuddin, Abu Seman Idris   +5 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Sensitization to oil palm pollen associates with risks and severity of allergic diseases

World Allergy Organization Journal
Background: Elaeis guineensis (Ela g, oil palm) pollen is one of the most predominant species of inhalant allergens in the tropical Southeast Asia region; however, its association with the manifestation of allergic diseases remains largely unexplored ...
Yang Yie Sio, Ph.D, Gallego Allaine Victoria Nanong, BSc (Hons), Jie Ann Lim, BSc (Hons), Sri Anusha Matta, Ph.D, Yee-How Say, Ph.D, Keng Foo Teh, MSc, Yi Ru Wong, BSc (Hons), Smyrna Moti Rawanan Shah, BSc (Hons), Kavita Reginald, Ph.D, Fook Tim Chew, Ph.D   +9 more
doaj   +1 more source

Advancing Fruit Bioimpedance Monitoring With Sustainable, Soft, And Bio‐Based Electrodes Beyond ECG

Advanced Electronic Materials, EarlyView.
Electrical impedance spectroscopy enables non‐destructive fruit quality monitoring, but conventional ECG and needle electrodes compromise signal stability, fruit physiology, and sustainability. This perspective highlights the transition toward soft, biocompatible, and biodegradable electrode interfaces based on natural substrates, bio‐derived ...
Sundus Riaz, Ahmed Rasheed, Angelo Zanella, Almudena Rivadeneyra, Paolo Lugli, Luisa Petti, Pietro Ibba   +6 more
wiley   +1 more source

Screening of Fungi from Oil Palm Rhizosphere in Peat Soils and the Potential as Biological Agents against Ganoderma boninense

Indonesian Journal of Agricultural Research, 2019
 One of the diseases that attack oil palm plants is stem rot disease. Control efforts that can be done is to use rhizosphere fungi from oil palm plants in peat soils.
Fifi Puspita, Isna Rahma Dini, Dermala Sari   +2 more
doaj   +3 more sources

Diseases of the Date Palm: Present Status and Future Prospects

Journal of Agricultural and Marine Sciences, 1998
While date palm is affected by many diseases, bayoud remains the most serious one. It is caused by a soil born pathogen, Fusarium oxyspurum f .sp. albedinis.
M. Djerbi
doaj   +1 more source

Partial Survey of Date Palm Dust Mite, Oligonychus afrasiaticus (McGregor) in Egypt Including Historical Trait [PDF]

Acarines: Journal of the Egyptian Society of Acarology, 2017
The economic importance of date palm tree Phoenix, dactylifera L. exceeds its nutrition value as the most valuable fruit. Preserve Egypt's international status as a large producer of dates in the world, requires tackling pests that attack palm trees ...
Hanaa El-Khateeb, M. Abou-Setta, Ashraf Elhalawany, A. Sanad   +3 more
doaj   +1 more source