Dupilumab treatment for Chinese Nagashima-type palmoplantar keratoderma associated with atopic dermatitis: a case report [PDF]
Frontiers in ImmunologyPatients with Nagashima-type palmoplantar keratoderma (NPPK) experience progressive, painful hyperkeratosis and fissuring of palms and soles that limits daily activities Due to the incomplete understanding of its pathogenesis, there are currently no ...
Chunting Hua
exaly +4 more sources
Palmoplantar Keratoderma: A Molecular Genetic Analysis of Family Cases [PDF]
International Journal of Molecular Sciences, 2022 Palmoplantar keratoderma is a clinically polymorphic disorder with a heterogeneous etiology characterized by marked hyperkeratotic lesions on the surface of palms and soles.
Tatiana Markova +2 more
exaly +3 more sources
Unique autosomal recessive variant of palmoplantar keratoderma associated with hearing loss not caused by known mutations [PDF]
Anais Brasileiros de Dermatologia, 2017 Inherited Palmoplantar Keratodermas are rare disorders of genodermatosis that are conventionally regarded as autosomal dominant in inheritance with extensive clinical and genetic heterogeneity.
Moustafa Abdelaal Hegazi +3 more
doaj +4 more sources
Palmoplantar keratoderma, pseudo-ainhum and knuckle pads in an African patient: A case report [PDF]
SAGE Open Medical Case Reports, 2023 Hereditary palmoplantar keratoderma is a rare heterogenous group of genodermatoses characterised by hyperkeratosis of the palms and soles. Genetic alterations affecting proteins of the keratin cytoskeleton, cornified cell envelope, desmosomes and gap ...
Kellicia Courtney Govender +1 more
doaj +2 more sources
Severe hereditary punctate palmoplantar keratoderma (Brauer-Buschke-Fischer syndrome) [PDF]
Przegląd Dermatologiczny, 2015 Introduction. Keratoderma of the hands and feet is a chronic disorder of epidermal keratinization, which consists of many various forms. Objective. To present a case of a 54-year-old woman with severe hereditary punctate palmoplantar keratoderma.
Dorota Jaśkiewicz-Nyckowska +3 more
doaj +2 more sources
Nivolumab Induced Palmoplantar Keratoderma [PDF]
Indian Dermatology Online JournalSingamsetty Sushma +3 more
doaj +4 more sources
Molecular insights into nagashima-type palmoplantar keratoderma: SERPINB7 mutation spectrum and mechanistic perspectives [PDF]
Frontiers in Molecular BiosciencesNagashima-type palmoplantar keratoderma (NPPK) is a common inherited palmoplantar keratoderma predominantly affecting East Asian populations and caused by biallelic loss-of-function variants in the SERPINB7 gene.
Zhenzhen Xiao +3 more
doaj +2 more sources
Palmoplantar keratoderma and associated syndromes
Seminars in Dermatology, 1995 This article focuses on the current state of knowledge concerning the characterization and classification of palmoplantar keratoderma and associated syndromes. In addition, therapeutic options are discussed. Exact diagnosis enables dermatologists to give patients accurate genetic counseling and may help to detect underlying defects or proneness to ...
Itin PH, Lautenschlager S
openaire +4 more sources
Clinical Dermatology ReviewPapillon–Lefevre syndrome is a rare autosomal recessive type of syndromic palmoplantar keratoderma, associated with ectodermal dysplasia. It is also known as keratoderma with periodontitis.
Sanjanaa Srinivasa +4 more
doaj +2 more sources
Aggressive Periodontitis and Palmoplantar Keratoderma: Papillon-Lefèvre Syndrome in an 11-Year-Old Nepalese Girl. [PDF]
Clin Case RepABSTRACT Papillon–Lefèvre syndrome is a rare autosomal recessive disorder characterized by palmoplantar keratoderma and aggressive periodontitis. We report an 11‐year‐old Nepalese girl presenting with severe periodontal destruction and characteristic cutaneous manifestations. Clinical and radiographic findings established the diagnosis.
Bhattarai J +3 more
europepmc +2 more sources