Results 231 to 240 of about 7,263 (276)

Prior Authorization, Quantity Limits, and Step Therapy for Patient-Administered Antiemetics.

open access: yesJAMA Netw Open
Vu K   +5 more
europepmc   +1 more source

Palonosetron

Drugs, 2004
Palonosetron is a potent and highly selective serotonin 5-HT(3) receptor antagonist that has been evaluated for the prevention of chemotherapy-induced nausea and vomiting. black triangle Intravenously administered palonosetron has a linear pharmacokinetic profile, with a long terminal elimination half-life ( approximate, equals 40 hours) and moderate ...
M Asif A, Siddiqui, Lesley J, Scott
  +5 more sources

Palonosetron

Reactions Weekly, 2009
Palonosetron is a second-generation serotonin 5-HT3 receptor antagonist, with a distinct pharmacological profile that differs from first-generation 5-HT3 receptor antagonists. Intravenous palonosetron is widely indicated for the prevention of chemotherapy-induced nausea and vomiting (CINV) in the acute and delayed phases following moderately emetogenic
Lily P H, Yang, Lesley J, Scott
openaire   +3 more sources

Effectiveness of Palonosetron, 1-Day Dexamethasone, and Aprepitant in Patients Undergoing Carboplatin-Based Chemotherapy

Oncology, 2023
Introduction: Dexamethasone (DEX)-sparing strategy with 5-hydroxytryptamine-3 receptor antagonist (5HT3RA) and aprepitant (APR), as triplet antiemetic prophylaxis, is associated with poor control of delayed chemotherapy-induced nausea and vomiting (CINV)
Toshinobu Hayashi   +6 more
semanticscholar   +1 more source

Impact of body weight-based dosing of palonosetron and ondansetron on postoperative nausea and vomiting following laparoscopic sleeve gastrectomy: a randomized, double-blind study

Acta Chirurgica Belgica, 2023
Background Postoperative nausea and vomiting (PONV) is a frequent adverse effect following laparoscopic sleeve gastrectomy. Palonosetron with a standard dosing (75 μg) schedule has been questioned due to its low efficiency in obese patients.
Buşra Burcu   +8 more
semanticscholar   +1 more source

Analysis of the Efficacy and Safety of Palonosetron Hydrochloride in Preventing Nausea And Vomiting After TACE: A Retrospective Analysis.

Current Radiopharmaceuticals, 2023
PURPOSE To investigate the mechanism of nausea and vomiting after TACE, and analyze the efficacy and safety of palonosetron hydrochloride in the prevention of nausea and vomiting after TACE.
Haohao Lu   +3 more
semanticscholar   +1 more source

Comparing Palonosetron and Ondansetron for Preventing Post-Operative Nausea and Vomiting in Abdominal Surgery Patients

International Journal of Pharmaceutical Quality Assurance
Background: Postoperative nausea and vomiting (PONV) is a frequent and distressing complication following abdominal surgeries, affecting patient comfort and recovery. Ondansetron and palonosetron, both serotonin 5HT3 receptor antagonists, are widely used
Devesh Shukla, Ranjeet Kumar
semanticscholar   +1 more source

Protective Effect of Palonosetron against Cisplatin-Induced Cytotoxicity via Decreased Phosphorylation of p38.

Biological and Pharmaceutical Bulletin
The dose-limiting nephrotoxicity of cisplatin (CDDP) is attributed to its accumulation in renal epithelial cells, mediated by uptake via human organic cation transporter 2 (hOCT2) and efflux via human multidrug and toxin extrusion 1 (hMATE1), followed by
Masayoshi Kondo   +4 more
semanticscholar   +1 more source

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