Results 241 to 250 of about 7,263 (276)

Randomized, Phase III Trial of Mixed Formulation of Fosrolapitant and Palonosetron (HR20013) in Preventing Cisplatin-Based Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: PROFIT

Journal of Clinical Oncology
PURPOSE Mixed formulation of fosrolapitant and palonosetron (PALO), HR20013, is a novel fixed-dose intravenous antiemetic combination that could simultaneously antagonize neurokinin-1 and 5-hydroxytryptamine-3 receptors.
Huaqiang Zhou, Yuanyuan Zhao, Mingjun Zhang, Jun Yao, Shuang Leng, Xiumin Li, Li Lin, Jinping Chen, Songnan Zhang, Xia Qin, Zhiquan Qin, T. Yi, Ruoyu Wang, Xiang Li, Yan Yu, Zhenghua Wang, Qinhong Zheng, Jiazhuan Mei, Aimin Zang, Na Li, Feng Cao, Ke Cao, Weiwei Li, Yan Lu, Dang Lin, Yan Zhou, Runxiang Yang, W. Fang, N. Zhou, Yunpeng Yang, Yaxiong Zhang, Gang Chen, Ting Zhou, Xue Yang, Huan Wang, Yujiao Wang, Yan Huang, Li Zhang   +37 more
semanticscholar   +1 more source

A Randomized, Controlled Trial of Palonosetron Versus Ondansetron for Nausea, Vomiting, and Pruritus in Cesarean Delivery with Intrathecal Morphine

Anesthesia and Analgesia
BACKGROUND: Spinal anesthesia is the preferred anesthetic technique for cesarean deliveries. Postoperative nausea and vomiting (PONV) and pruritus occur in up to 80% and 83% of patients, respectively, after cesarean delivery with intrathecal opioids ...
T. Worravitudomsuk, S. Charuluxananan, W. Sukumpanumet, P. Sriprajittichai   +3 more
semanticscholar   +1 more source

Fosrolapitant/Palonosetron: First Approval

Drugs
Simon Fung
openaire   +2 more sources

Cost-effectiveness of palonosetron and dexamethasone-based triple and quadruple regimens in preventing highly emetogenic chemotherapy-induced nausea and vomiting

Current Medical Research and Opinion, 2022
Objective Cost-effectiveness analyses that consider all currently used antiemetics in the case of emetogenic chemotherapy-induced nausea and vomiting (CINV) have not been performed yet. We aim to compare the cost-effectiveness of olanzapine (OLA), or/and
S. Halloush, Abdullah A. Alhifany, Nimer S. Alkhatib, A. Q. Al Bawab, Batool S Al-Qawasmeh, Esra'a Al Shawakri, J. Koeller   +6 more
semanticscholar   +1 more source

Intraoperative Prophylaxis with Palonosetron for Postoperative Nausea and/or Vomiting in Adults Undergoing Cardiothoracic Surgery Under General Anesthesia: A Single-Center Retrospective Study.

Journal of Cardiothoracic and Vascular Anesthesia
OBJECTIVE This study assessed the efficacy of palonosetron, alone or with dexamethasone, in reducing postoperative nausea and/or vomiting (PONV) and its impact on hospitalization duration in patients who undergo adult cardiothoracic surgery (CTS) under ...
Carlos E Estrada Alamo, Suejean Hwangpo, Lisa Chamberlain, Connie Chon, B. Nair, V. O’Reilly-Shah, Sarah E. Bain, Justin S. Liberman   +7 more
semanticscholar   +1 more source

Newer rp-hplc method development and validation for the simultaneous estimultaneous estimation of fosnetupitant and palonosetron in dosage form

International Journal of Pharmaceuticals and Health Care Research
A novel, precise, accurate, rapid and cost effective isocratic reversephase high performance liquid chromatographic (RP-HPLC) method was developed, optimized and validated for the estimation of Fosnetupitant and Palonosetron in bulk and pharmaceutical ...
Tadala Venkata Kaivalya, Buddha.Sravana Sree, Cheepurupalli Prasad   +2 more
semanticscholar   +1 more source

Comparison between Palonosetron and Ondansetron in Prevention of Chemotherapy Induced Nausea Vomiting

The Journal of Sylhet Women's Medical College
Background: Chemotherapy induced nausea and vomiting (CINV) is the commonest and the most incapacitating experience of thepatient undergoing cancer chemotherapy. Poorly controlled CINV sometimes make patients to refuse further treatment. This study aimed
Tanni TA
semanticscholar   +1 more source

PONV prophylaxis after laparoscopic procedures - Comparison between Palonosetron 0.075mg, Palonosetron 0.15mg and a Palonosetron-Dexamethasone combination : a randomised controlled trial

Acta Anaesthesiologica Belgica, 2020
Background : Postoperative nausea and vomiting (PONV) is one of the common complications after surgery. This randomized double-blind study was planned to compare the effectiveness of different antiemetic regimens for PONV prophylaxis in moderately high-risk patients.
N Bharti, N.B. Panda, K Kumari
openaire   +1 more source

Electrocardiographic findings of palonosetron in cancer patients

Supportive Care in Cancer, 2011
Nausea and vomiting are among the major problems occurring during and after the chemotherapy treatments of cancer patients. The recently developed 5-HT(3) antagonists have proved much more effective than former agents. Several studies have shown that these agents cause certain ECG changes.
Gonullu, Guzin, Demircan, Sabri, Demirag, Mustafa Kemal, Erdem, Dilek, Yucel, Idris   +4 more
openaire   +3 more sources

Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)

British Journal of Cancer, 2023
H. Minatogawa, Naoki Izawa, K. Shimomura, Hitoshi Arioka, H. Iihara, Mitsuhiro Sugawara, H. Morita, Ayako Mochizuki, S. Nawata, Keisuke Mishima, A. Tsuboya, T. Miyaji, Kazunori Honda, Ayako Yokomizo, Naoya Hashimoto, Takeshi Yanagihara, J. Endo, T. Kawaguchi, Naoki Furuya, Yumiko Sone, Y. Inada, Y. Ohno, C. Katada, N. Hida, Kana Akiyama, Daisuke Ichikura, Akiko Konomatsu, Takashi Ogura, Takuhiro Yamaguchi, T. Nakajima   +29 more
semanticscholar   +1 more source