Results 81 to 90 of about 24,642 (197)

Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice. [PDF]

, 2016
A152T-variant human tau (hTau-A152T) increases risk for tauopathies, including Alzheimer's disease. Comparing mice with regulatable expression of hTau-A152T or wild-type hTau (hTau-WT), we find age-dependent neuronal loss, cognitive impairments, and ...
Craft, Ryan, Davis, Allyson, Djukic, Biljana, Gill, T Michael, Guo, Weikun, Kim, Daniel, Lo, Iris, Maeda, Sumihiro, Masliah, Eliezer, Mucke, Lennart, Ponnusamy, Ravikumar, Taneja, Praveen, Wang, Xin, Yu, Gui-Qiu   +13 more
core   +2 more sources

Territorio y sociedad entre los Caya­pas del Siglo XVI

Anuario de Estudios Americanos, 1990
No disponible.
Josefina Palop Martínez
doaj   +1 more source

A debate: RFF derivada de la angiografía. Perspectiva desde la guía de presión

REC: Interventional Cardiology, 2020
PREGUNTA: ¿Qué posibles ventajas tiene respecto a la guía de presión y cuáles son las evidencias clínicas actuales de la reserva fraccional de flujo calculada por angiografía (angio-RFF)?
Ramón López Palop
doaj   +1 more source

Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments [PDF]

, 2015
Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition.
Berry, Colin, Corcoran, David, Hennigan, Barry, Layland, Jamie, Oldroyd, Keith G., Watkins, Stuart   +5 more
core   +1 more source

Teaching and Assessing Abstraction in K‐12 Computational Thinking Education: A Systematic Literature Review

Computer Applications in Engineering Education, Volume 33, Issue 5, September 2025.
ABSTRACT Abstraction is widely regarded as a fundamental skill in Computational Thinking (CT). However, the limited proficiency in abstraction demonstrated by undergraduate students when addressing algorithmic problems has prompted calls from researchers to explicitly integrate discussions on abstraction into early Computer Science education.
Annika Oser, Bernhard Standl
wiley   +1 more source

Genuine lab experiences for students in resource constrained environments: The RealLab with integrated intelligent assessment. [PDF]

, 2008
Laboratory activities are indispensable for developing engineering skills. Computer Aided Learning (CAL) tools can be used to enhance laboratory learning in various ways, the latest approach being the virtual laboratory technique that emulates ...
Azzi, Djamel, Chika, I., Haynes, B., Stocker, J.   +3 more
core   +1 more source

Impact of Dendritic Spine Loss on Excitability of Hippocampal CA1 Pyramidal Neurons: A Computational Study of Early Alzheimer Disease

Hippocampus, Volume 35, Issue 5, September 2025.
ABSTRACT Synaptic spine loss is an early pathophysiologic hallmark of Alzheimer disease (AD) that precedes overt loss of dendritic architecture and frank neurodegeneration. While spine loss signifies a decreased engagement of postsynaptic neurons by presynaptic targets, the degree to which loss of spines and their passive components impacts the ...
Chengju Tian, Isabel Reyes, Alexandra Johnson, Arjun V. Masurkar   +3 more
wiley   +1 more source

Comparison of Coronary Angiographic‐Derived and Intracoronary Imaging‐Based Fractional Flow Reserve in Assessing Coronary Artery Stenosis Severity: A Systematic Review and Network Meta‐Analysis

Journal of Evidence-Based Medicine, Volume 18, Issue 3, September 2025.
ABSTRACT Objective This systematic review and network meta‐analysis aimed to compare the accuracy of coronary angiographic‐derived fractional flow reserve (Angio‐FFR), optical coherence tomography (OCT)‐FFR, and intravascular ultrasound (IVUS)‐FFR in evaluating the severity of coronary artery stenosis.
Jianchang Xie, Lu Ye, Jianmin Yang, Yigang Zhong, Peng Xu, Beibei Gao, Ningfu Wang, Xianhua Ye, Guoxin Tong, Jinyu Huang   +9 more
wiley   +1 more source

El Reial decret llei 14/2019, el constrenyiment de les comunitats autònomes en matèria d’utilització d’eines digitals i electròniques i l’increment del control administratiu de l’opinió i de la informació en xarxes

Revista Catalana de Dret Públic, 2020
El present treball analitza les modificacions del nostre ordenament jurídic contingudes al Reial decret llei 14/2019 i els seus problemes tant jurídics com d’oportunitat.
Andrés Boix Palop
doaj   +1 more source

Safety and efficacy of a feed additive consisting of l‐lysine monohydrochloride produced with Corynebacterium glutamicumCGMCC 23982 for all animal species (Eppen Europe SAS) [PDF]

EFSA J
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l‐lysine monohydrochloride produced with a non‐genetically modified strain of Corynebacterium glutamicum (CGMCC 23982) as a nutritional additive to be used in feed and water for drinking for all animal species and ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Montserrat Anguita, Matteo L. Innocenti, Maria Kolona, Petr Letocha, Jordi Tarrés‐Call   +20 more
europepmc   +2 more sources