Results 101 to 110 of about 8,262 (240)

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Effect and length of doxycycline administration in elderly patients with bullous pemphigoid

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease and primarily affects the elderly. Systemic corticosteroids and immunosuppressive drugs are the standard treatment, but side effects often restrict their use. Doxycycline has been proposed as an alternative, but there is limited long‐term, real‐world data on its
Alena Merkel‐Ropele, Wolfgang Salmhofer, Peter Wolf   +2 more
wiley   +1 more source

Impact of diabetes mellitus on the menopausal experience: A scoping review

Diabetic Medicine, EarlyView.
Abstract Aims To identify, appraise and synthesise the current evidence relating to symptoms, experiences, management and impact of menopause on QoL among women with type 1 diabetes (T1DM) or type 2 diabetes (T2DM) and to identify evidence gaps. Methods We conducted a scoping review guided by Arksey and O'Mally's framework by searching CINAHL, MEDLINE,
Rachel Black, Felicity Hasson, Lisa King, Mark Davies, Deborah Muldrew, Paul Slater, Jenny Johnston, Dawn Adams, Rhonda Murphy, George Kernohan, Vivien Coates   +10 more
wiley   +1 more source

How to approach and manage palpitations in clinical practice

Palpitations are a common and often anxiety-provoking symptom for people who present in primary care. While many cases are benign, some indicate significant cardiac arrhythmia with potential haemodynamic compromise, highlighting the need for structured ...
Ahmed, Kawser, Alsararatee, Hasan H
core   +1 more source

Effectiveness of Adding GLP‐1 Receptor Agonists to SGLT2 Inhibitor Therapy in Chronic Kidney Disease: A Population Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Individually, sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP‐1RA and SGLT2i therapy in this population remains limited.
Hussain Salim, Shaheer Qureshi, Gaurav S. Gulsin, Habib R. Khan, Saad Ahmed Waqas, Gerry P. McCann, Amit Garg, Mohammed Shurrab, Kamlesh Khunti, Muhammad Rashid   +9 more
wiley   +1 more source

Safety and Utility of Smartphone‐Based Heart Monitors in Pediatric Patients With Cardiovascular Implantable Electronic Devices

Journal of Cardiovascular Electrophysiology, EarlyView.
Smartphone heart monitors in pediatric CIEDs: A pilot study. Smartphone heart monitors did not induce EMI in children with CIEDs, enabling reliable heart rate measurement and accurate identification of ventricular non‐captures. ABSTRACT Background Portable heart monitors enable on‐demand electrocardiogram (ECG) recordings and enhance symptom‐rhythm ...
Chun‐Lok Ho, Sit‐Yee Kwok, Sabrina S. L. Tsao, Yiu‐Fai Cheung   +3 more
wiley   +1 more source

Time‐Dependent Diagnostic Yield and Therapeutic Impact of Implantable Loop Recorders, Brugada Syndrome as the Exception

Journal of Cardiovascular Electrophysiology, EarlyView.
Diagnostic yield and therapeutic impact varied substantially according to the indication for implantation. Actionable diagnoses were concentrated in the early follow‐up period for syncope and palpitations, whereas late atrial fibrillation detection after cryptogenic stroke could still modify antithrombotic management. In contrast, patients with Brugada
Luigi Cocchiara, Benedetta Brescia, Procolo Marchese, Stefano Nardi, Luigi Argenziano, Gianmarco Arabia, Marco Micillo, Francesca Gennaro, Giovanni Mazzotta, Lucio Addeo, Alessandro Landolfi, Emiliano Calvi, Manuel Cerini, Alessio Nicolai, Teresa Strisciuglio, Pasquale Vergara, Giovanni Esposito, Antonio Rapacciuolo   +17 more
wiley   +1 more source

Holter monitoring - a necessity for the evaluation of palpitations

, 2017
Eighty-five patients complaining of palpitations were evaluated by means of 24-hour dynamic electrocardiography. A sensitivity of 0,69 and a specificity of 0,90 were calculated.
Smith, R, Diamond, T.H., Myburgh, D.P.
core  

A Comparison of Safety and Outcome Using Three Different Sedation Strategies During Pulsed Field Ablation for Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pulsed field ablation (PFA) is an emerging modality for atrial fibrillation (AF) ablation. However, adequate sedation of patients during treatment is imperative. Objective Our aim was to compare safety and outcome after deep sedation (DS) managed by electrophysiology staff (EP‐DS), DS by an anaesthesia nurse (AN‐DS), and general ...
Christina Alhede, Laurits Juhl Heinsen, Mille Ravn Sandgaard, Jacob Pontoppidan, Katrine Væsel Wade, Uffe Gang, Steen Buus Kristiansen, Arne Johannessen, Armin Osmanagic, Camilla Lundegaard Asferg, Peter Steen Hansen, Sam Riahi, Martin H. Ruwald, Peter Karl Jacobsen, Niels C. F. Sandgaard   +14 more
wiley   +1 more source