Results 41 to 50 of about 8,262 (240)

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

Straight Back Syndrome Presented with Chest and Back Pain: A Case Report

International Medical Case Reports Journal, 2022
Hiroshi Shiba,1 Tsuneaki Kenzaka2,3 1Department of Internal Medicine, Suwa Central Hospital, Chino, Japan; 2Department of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba, Japan; 3Division of Community Medicine and Career Development ...
Shiba H, Kenzaka T
doaj  

Persistence of Palpitations after Slow Pathway Modification for AVNRT in Young People

, 2021
Symptoms are the most common indication for ablation in children with atrioventricular nodal reentrant tachycardia (AVNRT). After the procedure, patients may continue to report palpitations.
Tsao, S, Ward, K, Desai, L, Carberry, T, Chaouki, AS, Webster, G, Stanley, S, Balmert, LC   +7 more
core   +1 more source

Characteristics Associated With Persistent Long COVID Symptoms in Healthcare Personnel Infected With SARS‐CoV‐2 Between August 2022 and May 2024: A Multicenter Cohort Analysis of US Healthcare Personnel

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz, Amanda K. Irish, Lilly C. Lee, Howard A. Smithline, Ian D. Plumb, Melissa Briggs‐Hagen, Alexandra F. Rollins, Karisa K. Harland, Anusha Krishnadasan, Karin F. Hoth, Eliezer Santos‐León, David A. Talan, Nicholas M. Mohr, Project PREVENT Network   +13 more
wiley   +1 more source

Progressive Thinning of the Basal Interventricular Septum by Giant Cell Myocarditis

JACC: Case Reports, 2020
We describe a patient with ventricular tachycardia and complete atrioventricular block. Remarkable thinning of the basal interventricular septum preceded left ventricular dysfunction. Endomyocardial biopsy demonstrated giant cell myocarditis. The patient
Arthur Iturriagagoitia, MD, Vanessa Meert, MD, Jeroen De Cocker, MD, Martin Penicka, MD, PhD, Ward Heggermont, MD, PhD, Marc Vanderheyden, MD   +5 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Palpitations and arrhythmia

, 2023
Palpitations are symptoms of a noticeable heartbeat, and they can feel like a fluttering, forceful, or sinking feeling in the chest. Due to their nature, many patients present with fears of a serious underlying cardiac disorder, leading to heightened ...
Scholfield, Steven, Priestner, Lucy
core   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Managing athletes with palpitations of unknown origin with an external loop recorder: a cohort study

, 2021
Background: Palpitations in athletes are usually benign, but the presence of major cardiac arrhythmias should be ruled out despite the infrequent appraisal of symptoms.
Penco, Maria, Cavarretta, Elena, Palamà, Zefferino, Siciliani, Stefania, Sette, Antonella, Grieco, Domenico, Romano, Silvio, Scarà, Antonio, Pelliccia, Antonio, Calò, Leonardo, DE Ruvo, Ermenegildo, Sciarra, Luigi, Nesti, Martina   +12 more
core   +2 more sources