Results 141 to 150 of about 190,027 (315)
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri+10 more
wiley +1 more source
GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration
Abstract INTRODUCTION We examined how abnormal prefrontal neurophysiology and changes in gamma‐aminobutyric acid‐ergic (GABAergic) neurotransmission contribute to behavioral impairments in disorders associated with frontotemporal lobar degeneration (FTLD). METHODS We recorded magnetoencephalography during an adaptive visuomotor task from 11 people with
Laura E. Hughes+11 more
wiley +1 more source
Transplantation of Entire Vertical Recti for Abducens Palsy [PDF]
Roderic O'Connor
openalex +1 more source
Objective Progressive Supranuclear Palsy (PSP) is a severe neurodegenerative disease characterized by tangles of hyperphosphorylated tau protein and tufted astrocytes. Developing treatments for PSP is challenging due to the lack of disease models reproducing its key pathological features.
Elvira Immacolata Parrotta+15 more
wiley +1 more source
Bridging the gap: reflections on co-creation in knowledge translation
Background To address the research-practice gap, knowledge translation is a crucial step in which co-creation, including patient and public involvement (PPI), is key.
Marjolijn Ketelaar+5 more
doaj +1 more source
Objective Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post‐mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive‐diagnosed with idiopathic PD have an alternative post ...
Lazzaro di Biase+2 more
wiley +1 more source
TWO CASES OF LEAD PALSY, WITH REMARKS ON THE DIAGNOSIS. [PDF]
Thomas Buzzard
openalex +1 more source
Deborah Gaebler-Spira, Michael Green
openaire +5 more sources
Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship
Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino+4 more
wiley +1 more source