Results 81 to 90 of about 533,400 (397)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Facial colliculus syndrome

CHRISMED Journal of Health and Research, 2016
A male patient presented with horizontal diplopia and conjugate gaze palsy. Magnetic resonance imaging (MRI) revealed acute infarct in right facial colliculus which is an anatomical elevation on the dorsal aspect of Pons.
Rupinderjeet Kaur, Paramdeep Singh, Krishan Singh Kajal, Simmi Aggarwal   +3 more
doaj   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Case Report: Hereditary neuropathy with liability to pressure palsy (HNPP): the role of genetic investigation in diagnostic assessment

Frontiers in Genetics
Hereditary neuropathy with liability to pressure palsies (HNPP) is a genetic disorder characterized by recurrent focal neuropathies typically occurring at sites of nerve entrapment or compression.
Salvatore Savasta, Fabiola Serra, Lucrezia Galimberti, Francesco Fabrizio Comisi, Marcello Cossu, Alessandro Vannelli, Maddalena Masala, Sara Tanca, Stefania Murru   +8 more
doaj   +1 more source

Soft Robotic Excretory Care Simulator for Nursing Education: Functional and Perceptual Biomimetics Approach

Advanced Robotics Research, EarlyView.
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa, Sota Suzuki, Shizuka Watanabe, Zebing Mao, Young Ah Seong, Toshinori Fujie, Tatsuhiro Horii, Kenjiro Tadakuma, Koichi Suzumori, Hiroyuki Nabae, Shingo Maeda   +10 more
wiley   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Conservative treatment of a psoas hematoma revealed by a lower limb palsy

The Pan African Medical Journal, 2017
The psoas hematoma is a rare complication of the anticoagulation therapy. It cause abdominal or lumbar pain, muscle dysfunction and sometimes nerve palsy. The optimal treatment is not well established, surgery or conservative treatment?
Zidouh Saad, Belkouch Ahmed, Rafai Mostafa, Bakkali Hicham, Belyamani Lahcen   +4 more
doaj   +1 more source

Current Approach to Obstetric Brachial Plexus Palsy

Medicine Science, 2015
Obstetrical brachial plexus palsy (BPP) is defined a flaccid paresis caused by damage of brachial plexus before or during delivery. Beyond 80-90% of patients may develop spontaneous remission; in 5-25% may develop lifelong disability. Recovery in 2 weeks
Tuba Tulay Koca
doaj   +1 more source

Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy

Brain : a journal of neurology, 2018
Prion-like, trans-neuronal spread of tau pathology in humans is controversial. By evaluating tau burden and functional connectivity in living patients, Cope et al.
T. Cope, T. Rittman, R. Borchert, P. Jones, D. Vatansever, K. Allinson, L. Passamonti, Patricia Vázquez Rodríguez, W. R. Bevan-Jones, J. O'Brien, James B. Rowe, James B. Rowe   +11 more
semanticscholar   +1 more source

Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review

Advanced Robotics Research, EarlyView.
This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj, Quan‐Chen Song, Jia‐Yang Juang   +2 more
wiley   +1 more source