Results 61 to 70 of about 19,195 (194)
Anticancer Research, 2019 Combination therapies are used in the clinic to achieve cure, better efficacy and to circumvent resistant disease in patients. Initial assessment of the effect of such combinations, usually of two agents, is frequently performed using in vitro assays. In
B. El Hassouni +10 more
semanticscholar +1 more source
Obesity, EarlyView.ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra +10 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen +10 more
wiley +1 more source
Control Strategy of Hardware-in-the-Loop Simulator EPOS 2.0 for Autonomous Docking Verification [PDF]
, 2011 This paper briefly describes the hybrid simulator system called European Proximity Operation Simulator (EPOS 2.0) and the development of the hardware-in-the-loop (HIL) docking simulation concept.
Boge, Toralf +3 more
core +1 more source
Histopathology, EarlyView.Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli +9 more
wiley +1 more source
Population PKPD of paclitaxel and carboplatin in ovarian cancer patients: A study by the EORTC‐PAMM‐NDDG [PDF]
British Journal of Clinical Pharmacology, 2007 Introduction: The paclitaxel/carboplatin doublet is standard treatment in advanced ovarian cancer and usually applied following cytoreductive surgery. Paclitaxel displays nonlinear PK, and the exposure‐toxicity relationship has been described by threshold‐models, whereas the time above a paclitaxel plasma concentration of 0.05–0.2 μmol/L (T>C0.05‐T&
M. Joerger +24 more
openaire +2 more sources
BMC Ophthalmology, 2021 Background We report one case of rare acute macular neuroretinopathy (AMN) in an elderly patient with hypertension and one case of common paracentral acute middle maculopathy (PAMM) in a patient with diabetes mellitus to illustrate the difference between
Qin Zhang, Xiuhong Qin, Ling Xu
doaj +1 more source
Fusion modeling in plasma physics: Vlasov-like systems
, 2010 The methods developed by authors are applied to some reductions of BBGKY hierarchy, namely, various examples of Vlasov-like systems which are important both for fusion modeling and for particular physical problems related to plasma/beam physics.
Chao, Davidson, Fedorova, Fedorova
core +1 more source
Gradient damage modeling of brittle fracture in an explicit dynamics context [PDF]
, 2016 International audienceIn this contribution we propose a dynamic gradient damage model as a phase-field approach for studying brutal fracture phenomena in quasi-brittle materials under impact-type loading conditions. Several existing approaches to account
Guilbaud, Daniel +3 more
core +2 more sources
Plant, Cell &Environment, EarlyView.ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source