Results 51 to 60 of about 66,691 (152)

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Modeling the dynamics of onchocerciasis using the Atangana–Baleanu fractional order with control measures

Scientific African
This study presents a fractional-order model using the Atangana–Baleanu–Caputo (ABC) derivative to analyze the spread and control of onchocerciasis. The model captures the memory effects inherent in the disease’s progression and includes human and vector
Nnaemeka Stanley Aguegboh, Daniel Ugochukwu Nnaji, Walter Okongo, Boubacar Diallo   +3 more
doaj   +1 more source

Life as an ethnic minority (EM) university student: Comparing mental health challenges among local and international EM students in Hong Kong

British Educational Research Journal, EarlyView.
Abstract University students globally face growing mental health challenges, with ethnic minority (EM) students—both local and international—being particularly vulnerable. Yet, limited research compares their experiences or identifies shared and distinct stressors, especially in non‐Western contexts.
Wang Xinyi, Naubahar Sharif
wiley   +1 more source

A state of the art review on energy management techniques and optimal sizing of DERs in grid-connected multi-microgrids

Cogent Engineering
In recent times, there has been a growing focus on multi-micro-grids (MMGs) system, owing to its well-suited structures for efficiently accommodating large-scale integration of distributed energy resources (DER).
Dessalegn Bitew Aeggegn, George Nyauma Nyakoe, Cyrus Wekesa   +2 more
doaj   +1 more source

Exploring the early observations of parents supporting their children with school attendance problems (SAPs): A co‐produced study

British Educational Research Journal, EarlyView.
Abstract School Attendance Problems (SAPs) represent a significant challenge requiring early identification and intervention. Current service provision often does not recognise early indicators that parents observe, creating gaps between when initial concerns are raised and formal support is provided.
Tereza Aidonopoulou‐Read, Michelle Pyer, Beth Bodycote, Jackie Campbell, Kirsteen Pyer   +4 more
wiley   +1 more source

Flight of the dragons: a global review of migration in Odonata

Biological Reviews, EarlyView.
ABSTRACT Insects are the most abundant and ecologically important animal migrants. Yet, we know relatively little about the patterns and processes underlying insect migration. Dragonflies (Anisoptera) and damselflies (Zygoptera) comprise the ancient insect order Odonata, whose ancestors were the first organisms to fly on Earth.
Johanna S.U. Hedlund, Myles Menz, Jason W. Chapman, Alexander Hayward   +3 more
wiley   +1 more source

Utterance evolution: the road to generative, combinatorial communicators

Biological Reviews, EarlyView.
ABSTRACT Language has long been considered uniquely complex in the animal kingdom; however, animal research over the last decade has begun to challenge some long‐standing premises about exactly which language capacities are uniquely human. The task of resolving why and how complex communication systems evolve, particularly human language, has ...
Catherine Crockford, Roman Martin Wittig, Cedric Girard‐Buttoz   +2 more
wiley   +1 more source

Spatial Assessment of Impacts of Artisanal and Small-scale Mining on Land Cover and Environment, Batouri, Eastern Cameroun

African Journal on Land Policy and Geospatial Sciences, 2019
Artisanal and small-scale mining affects the quality and components of the environment in the Batouri area in different ways. Activities interfere with air, soil, water, fauna and forest resources. This study seeks to assess the impacts of mining on the
NODEM FOMENE RODRIGUE
doaj   +1 more source

Partners or passengers? Revisiting the association between diatoms and aquatic animals

Biological Reviews, EarlyView.
ABSTRACT Numerous studies have revealed the importance of research on the communities capable of colonizing animal surfaces (epibionts) and the animals on which they live (basibionts). Very few studies have considered epizoic diatoms, and there are gaps and biases in our knowledge, including the choice of basibionts, the methods used, and the habitats ...
Gianluca Vacca, Elisa Falasco, Francesca Bona   +2 more
wiley   +1 more source