Results 91 to 100 of about 10,166 (220)

Metabolic fingerprinting of Angelica sinensis during growth using UPLC-TOFMS and chemometrics data analysis [PDF]

, 2013
BACKGROUND: The radix of Angelica sinensis is widely used as a medicinal herbal and metabolomics research of this plant during growth is necessary.
Hui Yan, Rina Sa, Xinbo Pan, Yali Wang, Yingwen Yang, Yiyun Qian, Yujing Sun   +6 more
core   +1 more source

17‐β‐Estradiol Protects Chondrocytes From Senescence and Ameliorates Osteoarthritis Progression via ERα‐AKT‐FOXO4 Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Osteoarthritis (OA) is a prevalent cause of joint pain in elderly individuals, and chondrocyte senescence plays a crucial role in its pathogenesis. FOXO4 has been identified as a crucial molecule in cellular senescence. However, little is known regarding its role in OA and the regulation of its expression.
Yikai Liu, Jiangshan Ai, Zian Zhang, Xinzhe Lu, Chaoqun Yu, Yejun Zha, Haining Zhang   +6 more
wiley   +1 more source

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source

Analysis of Microbial Diversity in Rhizosphere Soil of Panax notoginseng under Different Water and Microbial Fertilizer Conditions

Agronomy
Panax notoginseng is a highly regarded medicinal plant that has obstacles associated with continuous cropping. Understanding soil microorganisms is crucial, as they play a major role in this regard.
Leilei Yao, Lei Kong, Qiliang Yang, Hongjuan Nian, Jiaping Liang   +4 more
doaj   +1 more source

Effects of total saponins of Panax notoginseng on immature neuroblasts in the adult olfactory bulb following global cerebral ischemia/reperfusion

Neural Regeneration Research, 2015
The main active components extracted from Panax notoginseng are total saponins. They have been shown to inhibit platelet aggregation, increase cerebral blood flow, improve neurological behavior, decrease infarct volume and promote proliferation and ...
Xu He, Feng-jun Deng, Jin-wen Ge, Xiao-xin Yan, Ai-hua Pan, Zhi-yuan Li   +5 more
doaj   +1 more source

Borututu, artichoke and milk thistle: chemical profiles, antioxidant properties, anti-hepatocellular carcinoma activity and hepatotoxicity [PDF]

, 2014
Artichoke, borututu and milk thistle are medicinal plants widely consumed as infusions or included in dietary supplements for the treatment prevention of liver diseases.
Barros, Lillian, Ferreira, Isabel C.F.R., Pereira, Carla   +2 more
core   +1 more source

Interaction Between Clopidogrel and Panax Notoginseng Saponins

, 2020
Abstract Background: Panax notoginseng saponins (PNS) is commonly used in combination with clopidogrel in clinic. This study was to investigate the effect of PNS on the pharmacokinetics of clopidogrel active metabolite CAMD and the effect on the activities of clopidogrel metabolic enzymes in rats. Methods: In pharmacokinetics studies, the rats
Yunzhen Hu, Xi Yang
openaire   +1 more source

Unveiling Active Constituents and Potential Targets Related to the Hematinic Effect of Steamed Panax notoginseng Using Network Pharmacology Coupled With Multivariate Data Analyses

Frontiers in Pharmacology, 2019
Steamed Panax notoginseng (SPN) has been used as a tonic to improve the blood deficiency syndrome (BDS) in the theory of traditional Chinese medicine. Here, we aim to unveil active constituents and potential targets related to the hematinic effect of SPN,
Yin Xiong, Yin Xiong, Yin Xiong, Yupiao Hu, Lijuan Chen, Zejun Zhang, Yiming Zhang, Ming Niu, Xiuming Cui, Xiuming Cui, Xiuming Cui   +10 more
doaj   +1 more source

Lclet 4 enhances pro-apoptotic and anti-invasive effects of mitoxantrone on human prostate cancer cells : in vitro study [PDF]

, 2013
Triterpene saponosides are widely distributed plant secondary metabolites characterized by relatively low systemic cytotoxicity and a range of biological activities. These include anti-inflammatory, antimicrobial, vasoprotective and antitumor properties.
Czyż, Jarosław, Galanty, Agnieszka, Koczurkiewicz, Paulina, Madeja, Zbigniew, Michalik, Marta, Podolak, Irma, Wojcik, Katarzyna Anna   +6 more
core   +1 more source

Water management, planting slope indicators, and economic benefit analysis for Panax notoginseng production decision under shaded and rain-shelter cultivation: A three-year sloping fields experiment

Agricultural Water Management
Panax notoginseng cultivation planting conditions are harsh and require high soil moisture and slope of cultivated land, plus it takes 3–7 years from planting to harvesting. At present, the continuous crop barrier of Panax notoginseng has not been solved,
Jiankai Tang, Qiliang Yang, Jiaping Liang, Haidong Wang, Xiulu Yue   +4 more
doaj   +1 more source