Results 51 to 60 of about 6,144 (178)

Research Progress on Extraction, Structure, Biological Activity and Application of Panax notoginseng Saponin

Shipin gongye ke-ji
Panax notoginseng is a commonly used medicinal and edible plant in China. Panax notoginseng saponin is one of the main active ingredients of Panax notoginseng. It belongs to tetracyclic triterpenoid saponins.
Bingqi WEI, Liu CHEN, Xinyue ZHANG, Yanxin LIU, Yicui WANG   +4 more
doaj   +1 more source

Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Neurotoxic protein accumulation is widely recognized as a key feature of Alzheimer's disease (AD), and increasing evidence indicates that impaired brain clearance associated with dysfunction of the meningeal lymphatic and glymphatic may contribute to this process.
Jiheng Zhang, Jiren Zhang, Jian Ding, Xian Zhang, Yuhua Wang, Wei Wei, Yan Chai, Shu Zhang, Xin Chen   +8 more
wiley   +1 more source

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

Food Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan, Yau‐Yuen Chan, Guang Chen, Lin Xu, Cheng Zhang, Guoyi Tang, Yibin Feng, Ning Wang   +7 more
wiley   +1 more source

Protective effects of saponins in a rat model of severe acute pancreatitis occur through regulation of inflammatory pathway signaling by upregulation of miR-181b

International Journal of Immunopathology and Pharmacology, 2018
Panax notoginseng saponins are extracted from Chinese ginseng— Panax notoginseng Ledeb —and are known to have therapeutic anti-inflammatory effects. However, the precise mechanism behind their anti-inflammatory effects remains relatively unknown.
Ming-wei Liu, Yun-qiao Huang, Ya-ping Qu, Dong-mei Wang, Deng-yun Tang, Tian-wen Fang, Mei-xian Su, Yan-qiong Wang   +7 more
doaj   +1 more source

Using Network Pharmacology to Explore the Mechanism of Panax notoginseng in the Treatment of Myocardial Fibrosis

Journal of Diabetes Research, 2022
Objective. The mechanism of Panax notoginseng in treating myocardial fibrosis (MF) was investigated using network pharmacology. Methods. Effective ingredients and potential targets of Panax notoginseng were screened in relevant databases to construct a ...
Jingxue Han, Jingyi Hou, Yu Liu, Peng Liu, Tingting Zhao, Xinwei Wang   +5 more
doaj   +1 more source

Emerging Role of Panax ginseng in the Management of Cancer: Phytochemistry, SAR, Therapeutic Potential, and Clinical Aspects

Food Frontiers, Volume 7, Issue 3, May 2026.
This review aims to provide a comprehensive understanding of the therapeutic potential of bioactive anticancer phytoconstituents in Panax ginseng, including their clinical aspects and SAR, thereby fostering the development of newer anticancer compounds for cancer management.
Akrit Verma, Sanjeev Kumar Sahu, Anil Kumar Sah   +2 more
wiley   +1 more source

Panax notoginseng saponins improve recovery after spinal cord transection by upregulating neurotrophic factors

Neural Regeneration Research, 2015
Saponins extracted from Panax notoginseng are neuroprotective, but the mechanisms underlying this effect remain unclear. In the present study, we established a rat model of thoracic (T 10 ) spinal cord transection, and injected Panax notoginseng saponins
Bo Wang, Yu Li, Xuan-peng Li, Yang Li
doaj   +1 more source

Probiotic‐based strategies in vulvovaginal candidiasis management: A comprehensive review of mechanisms and future directions

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
This review focuses on vulvovaginal candidiasis (VVC), examining its epidemiology, the pathogenesis of Candida albicans, and its relationships with vaginal microbiota. It comprehensively reviews probiotic‐based management strategies and their mechanisms of action, and concludes by discussing current limitations, challenges and future research ...
Tong Chen, Yuwei Wu, Ya Chen, Ying Li, Hui Zhao, Lei Wu, He Gao, Tong Jiang, Xiaohong Wang, Moutong Chen, Jumei Zhang, Xinqiang Xie, Tingting Liang, Qingping Wu   +13 more
wiley   +1 more source

Microbes as carbendazim degraders: opportunity and challenge

Frontiers in Microbiology
Carbendazim (methyl benzimidazol-2-ylcarbamate, CBZ) is a systemic benzimidazole carbamate fungicide and can be used to control a wide range of fungal diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes.
Yi Zhou, Tianyue Wang, Liping Wang, Pengfei Wang, Feiyu Chen, Pankaj Bhatt, Shaohua Chen, Xiuming Cui, Ye Yang, Wenping Zhang   +9 more
doaj   +1 more source

Detection of Adulteration of Panax Notoginseng Powder by Terahertz Technology

Journal of Spectroscopy, 2022
The combined terahertz time-domain spectroscopy (THz-TDS) and chemometric technology is used to detect the adulteration of similar substances in Panax notoginseng powder.
Bin Li, Hai Yin, A-kun Yang, Ai-guo Ouyang   +3 more
doaj   +1 more source