Results 101 to 110 of about 855,009 (346)
Advanced Science, EarlyView.Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms [PDF]
, 2020 Wen-Cheng Chung +5 more
openalex +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity
Advanced Science, EarlyView.We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng +11 more
wiley +1 more source
AI‐Assisted Bioelectronics for Personalized Health Management
Advanced Electronic Materials, EarlyView.Recent advances in artificial intelligence (AI)‐assisted bioelectronics, including materials, device fabrication, working mechanisms, AI‐hardware integration, and proof‐of‐concept applications in digital health management, are summarized. The emergence of AI‐assisted bioelectronic systems and potential solutions to existing challenges are discussed ...
Huiwen Xiong +6 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Aim Spigelman stage IV duodenal polyposis (SP‐stage IV DP) is associated with high duodenal cancer risk in patients with familial adenomatous polyposis (FAP). This study evaluated the surgical and oncological outcomes of pancreas‐sparing total duodenectomy (PSTD) as a surgical prophylaxis for severe duodenal polyposis in FAP.
Takehiro Shiraishi +8 more
wiley +1 more source
Case Reports in Gastrointestinal Medicine, 2019 Cystic pancreatic neuroendocrine tumors represent around 13% of all neuroendocrine tumors (Hurtado-Pardo 2017). There has been an increase in the incidence of cases due to improvement in imaging modalities.
Iqra Haq +7 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background The annual number of pancreatoduodenectomies (PDs) in the United States has increased over the past decade, but the facility types driving this growth and whether outcomes have improved remain unclear. We aimed to identify characteristics of facilities with increasing PD volumes and assess national trends in centralization ...
Koichi Tomita, Naruhiko Ikoma
wiley +1 more source
Minimally invasive treatment of multiple complications of pancreatitis
Вестник хирургии имени И.И. ГрековаA clinical case of multiple complications of pancreatitis associated with intraductal pancreatic hypertension with the formation of a cyst of the head and body of the pancreas and, as a result, biliary hypertension in a 55-year-old patient is presented ...
R. G. Avanesyan +5 more
doaj +1 more source
Pancreatic lymphoepithelial cyst [PDF]
VideoGIE, 2017 Samuel, Sandeep +2 more
openaire +3 more sources