Results 111 to 120 of about 846,489 (348)

Intravenous iRGD‐Guided, RBC‐Membrane Camouflaged Lactococcus Lactis Remodels Cold NSCLC and Enhances PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen   +9 more
wiley   +1 more source

Pancreatic lymphoepithelial cyst [PDF]

open access: yesVideoGIE, 2017
Samuel, Sandeep   +2 more
openaire   +4 more sources

Polycystin‐1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1‐Dependent Microfilament Remodeling

open access: yesAdvanced Science, EarlyView.
Polycystin‐1 (PC1) senses collagen and ECM stiffness to promote tumor migration via Daam1‐mediated actin remodeling. A cleavage‐resistant PC1 mutant enhances YAP nuclear translocation and CTGF expression, which activates CAFs and further stiffens the ECM, forming a feed‐forward loop that drives tumor progression and metastasis.
Jiaofeng Zhou   +12 more
wiley   +1 more source

DIAGNOSIS OF EXOCRINE PANCREATIC INSUFFICIENCY IN CYSTIC FIBROSIS (CF) BY A SYNTHETIC PEPTIDE (Bz-Ty-PABA) [PDF]

open access: bronze, 1977
S Arvanitakis   +3 more
openalex   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

open access: yesAdvanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu   +20 more
wiley   +1 more source

Endoscopic Drainage of Pancreatic Pseudocysts

open access: yesCanadian Journal of Gastroenterology, 1990
Endoscopic drainage of pancreatic pseudocysts was attempted in 17 patients over an eight year period. There were nine cysts located in the head of the pancreas, six in the body and two in the tail.
Claude Liguory   +2 more
doaj   +1 more source

Monitoring Ca19-9 during pancreatic cyst surveillance: Better safe than sorry? [PDF]

open access: yesUnited European Gastroenterol J, 2023
Perri G, Vege SS, Marchegiani G.
europepmc   +1 more source

Deep Learning‐Powered Nanoplasmonic Biosensing Approach Enables Ultrasensitive Extracellular Vesicles Profiling for Cancer Screening

open access: yesAdvanced Science, EarlyView.
This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu   +21 more
wiley   +1 more source

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