Results 11 to 20 of about 10,302,641 (371)

Application of laparoscopic backtracking full-thickness continuous everting suture for non-AOSC choledocholithiasis

open access: yesBMC Surgery, 2023
Background Based on the current trend of increasing incidence of choledocholithiasis, it is of great significance to explore the closure method of the common bile duct during laparoscopic choledocholithotomy.
Bo Yuan   +4 more
doaj   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

open access: yesJournal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu   +12 more
doaj   +1 more source

Prognostic assessment capability of a five-gene signature in pancreatic cancer: a machine learning based-study

open access: yesBMC Gastroenterology, 2023
Background A prognostic assessment method with good sensitivity and specificity plays an important role in the treatment of pancreatic cancer patients.
Xuanfeng Zhang   +6 more
doaj   +1 more source

Identification of a novel miRNA-based recurrence and prognosis prediction biomarker for hepatocellular carcinoma

open access: yesBMC Bioinformatics, 2022
Background A high recurrence rate has always been a serious problem for treatment of hepatocellular carcinoma (HCC). Exploring predictors of postoperative and posttransplantation recurrence in patients with HCC can guide treatment strategies for ...
Xuanfeng Zhang   +4 more
doaj   +1 more source

Liver cirrhosis in Japan: Future global trends in the era of progressive antiviral therapy

open access: yesPortal Hypertension & Cirrhosis, 2022
In Japan, viral hepatitis is the main cause of chronic liver diseases, including liver cirrhosis. Due to the availability of highly effective antiviral drugs in combination with antihepatitis measures, Japan has become one of the most successful ...
Hirayuki Enomoto   +13 more
doaj   +1 more source

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma

open access: yesJournal of Translational Medicine, 2020
Background Cancer stem cells (CSCs) are crucial to the malignant behaviour and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). In recent years, CSC biology has been widely studied, but practical prognostic signatures based on CSC-related genes
Zengyu Feng   +6 more
doaj   +1 more source

A microprotein N1DARP encoded by LINC00261 promotes Notch1 intracellular domain (N1ICD) degradation via disrupting USP10-N1ICD interaction to inhibit chemoresistance in Notch1-hyperactivated pancreatic cancer

open access: yesCell Discovery, 2023
The extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for pancreatic cancer; however, few successful ...
Shuyu Zhai   +16 more
doaj   +1 more source

Real‐world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma

open access: yesCancer Medicine, 2023
Background The American Joint Committee on Cancer (AJCC) tumor‐node‐metastasis (TNM) staging system focuses on traditional biological factors (BFs). The present study incorporates nonbiological factors (NBFs) into the AJCC‐TNM staging system in terms of ...
Chao Wang   +4 more
doaj   +1 more source

Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation

open access: yesFrontiers in Immunology, 2022
Acinar cell death and inflammatory response are two important events which determine the severity of acute pancreatitis (AP). Endoplasmic reticulum (ER) stress and necroptosis are involved in this process, but the relationships between them remain ...
Xiao Han   +25 more
doaj   +1 more source

Pancreatic diseases [PDF]

open access: yesWiener Medizinische Wochenschrift, 2014
The author presents his personal choice of practical relevant papers of pancreatic diseases from 2014 to 2015. Nutritional factors and hypertriglycidemia are discussed as causes of acute pancreatitis. Tools to avoid post-ERCP(endoscopic retrograde cholangiopancreatography) pancreatitis are described and the natural course of fluid collections and ...
openaire   +3 more sources

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