Results 11 to 20 of about 646,520 (340)

Diagnosis of pancreatic disease in feline platynosomosis. [PDF]

J Feline Med Surg, 2017
Objectives: Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal ...
Köster LS, Shell L, Ketzis J, Rajeev S, Illanes O.   +4 more
europepmc   +3 more sources

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma

Journal of Translational Medicine, 2020
Background Cancer stem cells (CSCs) are crucial to the malignant behaviour and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). In recent years, CSC biology has been widely studied, but practical prognostic signatures based on CSC-related genes
Zengyu Feng, Minmin Shi, Kexian Li, Yang Ma, Lingxi Jiang, Hao Chen, Chenghong Peng   +6 more
doaj   +1 more source

A microprotein N1DARP encoded by LINC00261 promotes Notch1 intracellular domain (N1ICD) degradation via disrupting USP10-N1ICD interaction to inhibit chemoresistance in Notch1-hyperactivated pancreatic cancer

Cell Discovery, 2023
The extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for pancreatic cancer; however, few successful ...
Shuyu Zhai, Jiewei Lin, Yuchen Ji, Ronghao Zhang, Zehui Zhang, Yizhi Cao, Yang Liu, Xiaomei Tang, Jia Liu, Pengyi Liu, Jiayu Lin, Fanlu Li, Hongzhe Li, Yusheng Shi, Da Fu, Xiaxing Deng, Baiyong Shen   +16 more
doaj   +1 more source

Real‐world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma

Cancer Medicine, 2023
Background The American Joint Committee on Cancer (AJCC) tumor‐node‐metastasis (TNM) staging system focuses on traditional biological factors (BFs). The present study incorporates nonbiological factors (NBFs) into the AJCC‐TNM staging system in terms of ...
Chao Wang, Haoda Chen, Xiaxing Deng, Wei Xu, Baiyong Shen   +4 more
doaj   +1 more source

Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation

Frontiers in Immunology, 2022
Acinar cell death and inflammatory response are two important events which determine the severity of acute pancreatitis (AP). Endoplasmic reticulum (ER) stress and necroptosis are involved in this process, but the relationships between them remain ...
Xiao Han, Xiao Han, Bin Li, Bin Li, Jingpiao Bao, Jingpiao Bao, Zengkai Wu, Zengkai Wu, Congying Chen, Congying Chen, Jianbo Ni, Jianbo Ni, Jie Shen, Jie Shen, Pengli Song, Pengli Song, Qi Peng, Qi Peng, Rong Wan, Rong Wan, Xingpeng Wang, Xingpeng Wang, Jianghong Wu, Jianghong Wu, Guoyong Hu, Guoyong Hu   +25 more
doaj   +1 more source

TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma

Journal of Translational Medicine, 2023
Background Although the molecular features of pancreatic ductal adenocarcinoma (PDAC) have been well described, the impact of detailed gene mutation subtypes on disease progression remained unclear.
Yiran Zhou, Jiabin Jin, Yuchen Ji, Jiaqiang Zhang, Ningzhen Fu, Mengmin Chen, Jun Wang, Kai Qin, Yu Jiang, Dongfeng Cheng, Xiaxing Deng, Baiyong Shen   +11 more
doaj   +1 more source

Pancreatic diseases [PDF]

Wiener Medizinische Wochenschrift, 2014
The author presents his personal choice of practical relevant papers of pancreatic diseases from 2014 to 2015. Nutritional factors and hypertriglycidemia are discussed as causes of acute pancreatitis. Tools to avoid post-ERCP(endoscopic retrograde cholangiopancreatography) pancreatitis are described and the natural course of fluid collections and ...
openaire   +3 more sources

Staging chronic pancreatitis with exocrine function tests: Are we better? [PDF]

, 2017
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas evolving in progressive fibrotic disruption of the gland with exocrine and endocrine pancreatic insufficiency.
MOLETTA, LUCIA, SPERTI, COSIMO
core   +1 more source

Oncogene APOL1 promotes proliferation and inhibits apoptosis via activating NOTCH1 signaling pathway in pancreatic cancer

Cell Death and Disease, 2021
APOL1 encodes a secreted high-density lipoprotein, which has been considered as an aberrantly expressed gene in multiple cancers. Nevertheless, the role of APOL1 in the regulatory mechanisms of pancreatic cancer remains unknown and should be explored. We
Jiewei Lin, Zhiwei Xu, Junjie Xie, Xiaxing Deng, Lingxi Jiang, Hao Chen, Chenghong Peng, Hongwei Li, Jiaqiang Zhang, Baiyong Shen   +9 more
doaj   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources