Results 11 to 20 of about 9,990,963 (401)

A Prognostic Model Based on RNA Binding Protein Predicts Clinical Outcomes in Hepatocellular Carcinoma Patients

Frontiers in Oncology, 2021
Dysregulation of RNA binding proteins (RBPs) is closely associated with tumor events. However, the function of RBPs in hepatocellular carcinoma (HCC) has not been fully elucidated.
Zhongsong Man, Yongqiang Chen, Lu Gao, Guowei Xei, Quanfu Li, Qian Lu, Jun Yan   +6 more
doaj   +1 more source

Application of laparoscopic backtracking full-thickness continuous everting suture for non-AOSC choledocholithiasis

BMC Surgery, 2023
Background Based on the current trend of increasing incidence of choledocholithiasis, it is of great significance to explore the closure method of the common bile duct during laparoscopic choledocholithotomy.
Bo Yuan, Xuanfeng Zhang, Chenchen Kong, Cancan Zhang, Huansong Li   +4 more
doaj   +1 more source

LncRNA-PACERR induces pro-tumour macrophages via interacting with miR-671-3p and m6A-reader IGF2BP2 in pancreatic ductal adenocarcinoma

Journal of Hematology & Oncology, 2022
Background LncRNA-PACERR plays critical role in the polarization of tissue-associated macrophages (TAMs). In this study, we found the function and molecular mechanism of PACERR in TAMs to regulate pancreatic ductal adenocarcinoma (PDAC) progression ...
Yihao Liu, Minmin Shi, Xingfeng He, Yizhi Cao, Pengyi Liu, Fanlu Li, Siyi Zou, Chenlei Wen, Qian Zhan, Zhiwei Xu, Jiancheng Wang, Baofa Sun, Baiyong Shen   +12 more
doaj   +1 more source

The role of pancreatic polypeptide in pancreatic diseases [PDF]

Advances in Clinical and Experimental Medicine, 2017
The aim of this study was to review the diagnostic significance of pancreatic polypeptide (PP) in pancreatic diseases. PP may play a significant role in monitoring the development of the disease and the patient's healing process, particularly after the removal of a portion of the pancreas. Determining PP in acute pancreatitis is quite controversial. At
Grzegorz Marek, Mariola Śliwińska-Mossoń, Halina Milnerowicz   +2 more
openaire   +3 more sources

Prognostic assessment capability of a five-gene signature in pancreatic cancer: a machine learning based-study

BMC Gastroenterology, 2023
Background A prognostic assessment method with good sensitivity and specificity plays an important role in the treatment of pancreatic cancer patients.
Xuanfeng Zhang, Lulu Yang, Dong Zhang, Xiaochuan Wang, Xuefeng Bu, Xinhui Zhang, Long Cui   +6 more
doaj   +1 more source

Identification of a novel miRNA-based recurrence and prognosis prediction biomarker for hepatocellular carcinoma

BMC Bioinformatics, 2022
Background A high recurrence rate has always been a serious problem for treatment of hepatocellular carcinoma (HCC). Exploring predictors of postoperative and posttransplantation recurrence in patients with HCC can guide treatment strategies for ...
Xuanfeng Zhang, Dong Zhang, Xuefeng Bu, Xinhui Zhang, Long Cui   +4 more
doaj   +1 more source

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma

Journal of Translational Medicine, 2020
Background Cancer stem cells (CSCs) are crucial to the malignant behaviour and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). In recent years, CSC biology has been widely studied, but practical prognostic signatures based on CSC-related genes
Zengyu Feng, Minmin Shi, Kexian Li, Yang Ma, Lingxi Jiang, Hao Chen, Chenghong Peng   +6 more
doaj   +1 more source

Liver cirrhosis in Japan: Future global trends in the era of progressive antiviral therapy

Portal Hypertension & Cirrhosis, 2022
In Japan, viral hepatitis is the main cause of chronic liver diseases, including liver cirrhosis. Due to the availability of highly effective antiviral drugs in combination with antihepatitis measures, Japan has become one of the most successful ...
Hirayuki Enomoto, Tomoyuki Takashima, Takashi Nishimura, Nobuhiro Aizawa, Naoto Ikeda, Yukihisa Yuri, Mamiko Okamoto, Kohei Yoshihara, Ryota Yoshioka, Shoki Kawata, Shogo Ota, Ryota Nakano, Hideyuki Shiomi, Hiroko Iijima   +13 more
doaj   +1 more source

Pancreatic Cancer: Changing Epidemiology and New Approaches to Risk assessment, Early Detection, and Prevention.

Gastroenterology, 2023
Pancreatic cancer usually results in poor survival with limited options for treatment, as most affected individuals present with advanced disease. Early detection of pre-invasive pancreatic neoplasia and identifying molecular therapeutic targets provide ...
E. Stoffel, R. Brand, M. Goggins
semanticscholar   +1 more source

A microprotein N1DARP encoded by LINC00261 promotes Notch1 intracellular domain (N1ICD) degradation via disrupting USP10-N1ICD interaction to inhibit chemoresistance in Notch1-hyperactivated pancreatic cancer

Cell Discovery, 2023
The extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for pancreatic cancer; however, few successful ...
Shuyu Zhai, Jiewei Lin, Yuchen Ji, Ronghao Zhang, Zehui Zhang, Yizhi Cao, Yang Liu, Xiaomei Tang, Jia Liu, Pengyi Liu, Jiayu Lin, Fanlu Li, Hongzhe Li, Yusheng Shi, Da Fu, Xiaxing Deng, Baiyong Shen   +16 more
doaj   +1 more source