Results 51 to 60 of about 646,520 (340)

Plasminogen in Pancreatic Disease and in Pancreatic Secretion

open access: yesExperimental Biology and Medicine, 1957
Summary1. Serum plasminogen and amylase levels were measured in 12 dogs in whom pancreatic necrosis and/or fat necrosis was produced. An increase of plasminogen along with the expected increase in amylase was noted under the conditions described. 2. Samples of pure pancreatic juice obtained from 4 dogs were tested for the presence of plasminogen.
Anna B. Bridgwater, Heinrich Necheles
openaire   +3 more sources

Primary leiomyosarcoma of the pancreas: report of a case treated by local excision and review of the literature [PDF]

open access: yes, 2015
First described by Ross in 1951, primary pancreatic leiomyosarcoma is a rare mesenchymal tumour of the pancreas, with nonspecific clinical and radiological features and a poor prognosis, if ...
Blandamura, Stella   +3 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy

open access: yesSignal Transduction and Targeted Therapy, 2021
Despite great success in cancer immunotherapy, immune checkpoint-targeting drugs are not the most popular weapon in the armory of cancer therapy. Accumulating evidence suggests that the tumor immune microenvironment plays a critical role in anti-cancer ...
Tianyu Tang   +5 more
doaj   +1 more source

A current perspective on stereotactic body radiation therapy for pancreatic cancer. [PDF]

open access: yes, 2016
Pancreatic cancer is a formidable malignancy with poor outcomes. The majority of patients are unable to undergo resection, which remains the only potentially curative treatment option.
Czito, Brian G   +3 more
core   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Obesity and Pancreatic Diseases

open access: yesThe Korean Journal of Gastroenterology, 2012
Obesity is defined as BMI (calculated as weight in kg divided by height in m2) more than 30, and overweight is defined as BMI of 25-29.9. Obesity has been considered as a risk factor for pancreatic diseases, including pancreatitis and pancreatic cancer. Severe acute pancreatitis is significantly more frequent in obese patients.
Ho Gak Kim, Jimin Han
openaire   +2 more sources

Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]

open access: yes, 2001
Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Impact of perioperative immunonutrition on postoperative outcomes in pancreaticoduodenectomy: a systematic review and meta-analysis of randomized controlled trials

open access: yesBMC Gastroenterology
Background This systematic review and meta-analysis aimed to evaluate the impact of perioperative immunonutrition on postoperative outcomes in patients undergoing pancreaticoduodenectomy (PD).
Gaofeng Zhang   +6 more
doaj   +1 more source

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