Results 51 to 60 of about 9,801,285 (428)

Equine pancreatic disease

Journal of Veterinary Diagnostic Investigation, 2015
Equine pancreatic disease is considered rare, and successful treatment is limited. Additionally, antemortem diagnosis of equine pancreatitis is difficult because of the lack of definitive diagnostic tests. Although a paucity of information exists on this
S. Newman
semanticscholar   +1 more source

Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts. [PDF]

, 2019
Pancreatic cancer is a complex disease, in need of new therapeutic approaches. In this study, we explored the effect and mechanism of action of epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, alone and in combination with current ...
Hackman, Robert M, Mackenzie, Gerardo G, Wang, Yuefei, Wei, Ran   +3 more
core   +1 more source

SARS-CoV2 RNA detection in a pancreatic pseudocyst sample [PDF]

, 2020
The involvement of gastrointestinal system in SARS-CoV2 related disease, COVID-19, is increasingly recognized. COVID-19 associated pancreatic injury has been suggested, but its correlation with pancreatic disease is still unclear. In this case report, we
Annibale B., Cattani P., De Biase L., Larghi A., Miele L., Panzuto F., Papa A., Rapaccini G. L., Schepis T.   +8 more
core   +1 more source

CTG-Net: An Efficient Cascaded Framework Driven by Terminal Guidance Mechanism for Dilated Pancreatic Duct Segmentation [PDF]

arXiv, 2023
Pancreatic duct dilation indicates a high risk of various pancreatic diseases. Segmentation of dilated pancreatic ducts on computed tomography (CT) images shows the potential to assist the early diagnosis, surgical planning and prognosis. Because of the ducts' tiny sizes, slender tubular structures and the surrounding distractions, most current ...
arxiv  

Evidence for a Causal Relationship Between Early Exocrine Pancreatic Disease and Cystic Fibrosis–Related Diabetes: A Mendelian Randomization Study

Diabetes, 2014
Circulating immunoreactive trypsinogen (IRT), a biomarker of exocrine pancreatic disease in cystic fibrosis (CF), is elevated in most CF newborns. In those with severe CF transmembrane conductance regulator (CFTR) genotypes, IRT declines rapidly in the ...
David Soave, Melissa R. Miller, K. Keenan, Weili Li, Jiafen Gong, W. Ip, F. Accurso, Lei Sun, J. Rommens, M. Sontag, P. Durie, L. Strug   +11 more
semanticscholar   +1 more source

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance We describe a biobank of patient-derived pancreatic cancer organoids, characterized by whole-genome DNA sequencing, RNA sequencing, and histology.
E. Driehuis, E. Driehuis, A. Hoeck, A. Hoeck, Kat S. Moore, S. Kolders, Sigrid Kolders, Hayley E. Francies, M. Gulersonmez, E. Stigter, B. Burgering, Veerle Geurts, Veerle Geurts, A. Gračanin, G. Bounova, F. Morsink, R. Vries, S. Boj, J. V. Es, J. V. Es, G. Offerhaus, O. Kranenburg, M. Garnett, L. Wessels, Edwin Cuppen, Edwin Cuppen, L. Brosens, H. Clevers, Hans Clevers   +28 more
semanticscholar   +1 more source

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. [PDF]

, 2015
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal prognosis. However, while most patients die within the first year of diagnosis, very rarely, a few patients can survive for >10 years.
Brentnall, Teresa A, Chen, Ru, Crispin, David A, Dawson, David W, de Wilde, Roeland F, Lai, Lisa A, Lay, Anna R, Maitra, Anirban, May, Damon H, McIntosh, Martin W, Ottenhof, Niki A, Pan, Sheng, Simeone, Diane M, Waghray, Meghna, Wang, Shouli, Wolfgang, Christopher L   +15 more
core   +1 more source

Runx3-overexpression cooperates with ex vivo AKT inhibition to generate receptor-engineered T cells with better persistence, tumor-residency, and antitumor ability

Journal for ImmunoTherapy of Cancer, 2023
Background Solid tumors pose unique roadblocks to treatment with chimeric antigen receptor (CAR) T cells, including limited T-cell persistence, inefficient tumor infiltration, and an immunosuppressive tumor microenvironment. To date, attempts to overcome
Qi Zhang, Jiangchao Wu, Tingbo Liang, Xueli Bai, Xun Wang, Jianpeng Sheng, Junlei Zhang, Jianghui Tang, Jinyuan Song, Yongtao Ji   +9 more
doaj   +1 more source

Pancreatic Cancer: A Review.

Journal of the American Medical Association (JAMA), 2021
Importance Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer, with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of PDAC is increasing by 0.5% to 1.0% per year, and it is projected to become the second-
Wungki Park, A. Chawla, E. O’Reilly
semanticscholar   +1 more source

Peribiliary glands as a niche of extra-pancreatic precursors yielding insulin-producing cells in experimental and human diabetes [PDF]

, 2016
Peribiliary glands (PBGs) are niches in the biliary tree and containing heterogeneous endodermal stem/progenitors cells that can differentiate, in vitro and in vivo, towards pancreatic islets.
Alvaro, Domenico, Berloco, Pasquale Bartolomeo, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, GINANNI CORRADINI, Stefano, Maroder, Marella, Nevi, Lorenzo, Puca, Rosa, Reid, Lola M, Renzi, Anastasia, Rossi, Massimo, Scafetta, Gaia   +12 more
core   +1 more source