Results 61 to 70 of about 9,990,963 (401)

Who could complete and benefit from the adjuvant chemotherapy regarding pancreatic ductal adenocarcinoma? A multivariate‐adjusted analysis at the pre‐adjuvant chemotherapy timing

open access: yesCancer Medicine, 2022
Background The pre‐adjuvant chemotherapy (PAC) status of postoperative pancreatic ductal adenocarcinoma (PDAC) patients has not been studied and elaborated well previously.
Ningzhen Fu   +6 more
doaj   +1 more source

Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance.

open access: yesAnnual Review of Pathology, 2022
Pancreatic ductal adenocarcinoma (PDAC) features a prominent stromal microenvironment with remarkable cellular and spatial heterogeneity that meaningfully impacts disease biology and treatment resistance.
M. Sherman, G. Beatty
semanticscholar   +1 more source

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management. [PDF]

open access: yes, 2017
Pancreatic cancer is one the most lethal malignancies. Only a small proportion of patients with this disease benefit from surgery. Chemotherapy provides only a transient benefit.
Michael Pimienta   +4 more
core   +2 more sources

Common Pancreatic Disease [PDF]

open access: yes, 2010
Pancreatitis is an inflammatory disease of the pancreas characterized by acute and chronic condition as well as varying duration and severity. Acute pancreatitis (AP) is a severe abdominal inflammation, characterized by parenchymal edema, necrosis with occasional presence of pseudocysts, abscess, hemorrhage, and inflammatory cell infiltration.
openaire   +3 more sources

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1

open access: yesJournal of Hematology & Oncology, 2022
Background circRNA has been established to play a pivotal role in tumorigenesis development in a variety of cancers; nevertheless, the biological functions and molecular mechanisms of hypoxia-induced exosomal circRNAs in pancreatic cancer remain largely ...
Jiewei Lin   +8 more
doaj   +1 more source

Prognostic factors of survival in patients treated with nab-paclitaxel plus gemcitabine regimen for advanced or metastatic pancreatic cancer: A single institutional experience. [PDF]

open access: yes, 2015
The objectives of this study were to evaluate the effectiveness of nab-paclitaxel plus gemcitabine (NAB-P/GEM) regimen in an unselected population of patients with advanced inoperable or metastatic pancreatic cancer (PC), and to identify the prognostic ...
Basso, Smm   +5 more
core   +2 more sources

Nonalcoholic fatty pancreatic disease and cardio-metabolic risk: is there is a place for obstructive sleep apnea?

open access: yesCardiovascular Diabetology, 2014
BackgroundObstructive sleep apnea is a common disorder acting as a risk factor for the development and progression of cardiometabolic derangements including non-alcoholic fatty liver disease.
A. Mirrakhimov
semanticscholar   +1 more source

Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]

open access: yes, 2001
Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
core   +1 more source

Plasminogen in Pancreatic Disease and in Pancreatic Secretion

open access: yesExperimental Biology and Medicine, 1957
Summary1. Serum plasminogen and amylase levels were measured in 12 dogs in whom pancreatic necrosis and/or fat necrosis was produced. An increase of plasminogen along with the expected increase in amylase was noted under the conditions described. 2. Samples of pure pancreatic juice obtained from 4 dogs were tested for the presence of plasminogen.
Anna B. Bridgwater, Heinrich Necheles
openaire   +3 more sources

Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy

open access: yesSignal Transduction and Targeted Therapy, 2021
Despite great success in cancer immunotherapy, immune checkpoint-targeting drugs are not the most popular weapon in the armory of cancer therapy. Accumulating evidence suggests that the tumor immune microenvironment plays a critical role in anti-cancer ...
Tianyu Tang   +5 more
doaj   +1 more source

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