Results 81 to 90 of about 9,801,285 (428)

The great pretender : Autoimmune Pancreatitis [PDF]

open access: yes, 2014
Autoimmune pancreatitis is a benign disorder which frequently presents with symptoms and imaging suggestive of pancreatic malignancy. Up to 21% of pancreatoduodenectomies performed for suspected pancreatic cancer are found to have benign disease ...
Azzopardi, Neville
core  

Para-aortic node involvement is not an independent predictor of survival after resection for pancreatic cancer [PDF]

open access: yes, 2017
AIM To analyze the importance of para-aortic node status in a series of patients who underwent pancreaticoduodenectomy (PD) in a single Institution.
Beltrame, Valentina   +7 more
core   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy

open access: yesSignal Transduction and Targeted Therapy, 2021
Despite great success in cancer immunotherapy, immune checkpoint-targeting drugs are not the most popular weapon in the armory of cancer therapy. Accumulating evidence suggests that the tumor immune microenvironment plays a critical role in anti-cancer ...
Tianyu Tang   +5 more
doaj   +1 more source

Tumorigenesis and axons regulation for the pancreatic cancer: a mathematical approach [PDF]

open access: yesarXiv, 2022
The nervous system is today recognized to play an important role in the development of cancer. Indeed, neurons extend long processes (axons) that grow and infiltrate tumors in order to regulate the progression of the disease in a positive or negative way, depending on the type of neuron considered.
arxiv  

ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium.

open access: yesOncology Report, 2013
There is strong epidemiologic evidence indicating that common genetic variability could be implicated in pancreatic cancer risk and, to date, various loci have been proposed.
C. Rizzato   +23 more
semanticscholar   +1 more source

Sotorasib in KRAS p.G12C-Mutated Advanced Pancreatic Cancer.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND KRAS p.G12C mutation occurs in approximately 1 to 2% of pancreatic cancers. The safety and efficacy of sotorasib, a KRAS G12C inhibitor, in previously treated patients with KRAS p.G12C-mutated pancreatic cancer are unknown.
J. Strickler   +21 more
semanticscholar   +1 more source

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]

open access: yes, 2018
Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation.
Amirfakhri, Siamak   +12 more
core  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Impact of perioperative immunonutrition on postoperative outcomes in pancreaticoduodenectomy: a systematic review and meta-analysis of randomized controlled trials

open access: yesBMC Gastroenterology
Background This systematic review and meta-analysis aimed to evaluate the impact of perioperative immunonutrition on postoperative outcomes in patients undergoing pancreaticoduodenectomy (PD).
Gaofeng Zhang   +6 more
doaj   +1 more source

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