Results 201 to 210 of about 466,398 (341)

Obesity and Pancreatic Diseases: From Inflammation to Oncogenesis and the Impact of Weight Loss Interventions. [PDF]

Nutrients
Souto M, Cúrdia Gonçalves T, Cotter J.
europepmc   +1 more source

Impact of the COVID-19 Pandemic on the Management of Gallbladder, Biliary Tract, and Pancreatic Diseases. [PDF]

Cureus, 2023
Ilyas Khan A, Thomas C, O'Connor H, Dowker F, Horgan L, Khan MA.   +5 more
europepmc   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis. [PDF]

World J Gastroenterol
Tornel Avelar AI, Gerrard CN, Priego Parra BA.   +2 more
europepmc   +1 more source

Optimal glycated hemoglobin A1c value for prediabetes and diabetes in patients with pancreatic diseases. [PDF]

Front Endocrinol (Lausanne), 2023
Chen G, Zhang R, Tan C, Liu X, Yu L, Chen Y.   +5 more
europepmc   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

The role of autophagy in pancreatic diseases. [PDF]

Front Pharmacol
Zhang WG, Wu QZ, Shao BZ.
europepmc   +1 more source

Understanding Necroptosis in Pancreatic Diseases. [PDF]

Biomolecules, 2022
He R, Wang Z, Dong S, Chen Z, Zhou W.
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

European Registry of Hereditary Pancreatic Diseases (EUROPAC): protocol for primary and secondary screening in individuals with inherited pancreatic disease syndromes for pancreatic ductal adenocarcinoma and complications of other pancreatic diseases. [PDF]

BMJ Open
Boughey A, Hopley P, Sarantitis I, Thomas P, Gubacsi B, Jevons K, Crowe E, Hughes E, Quinn I, Royle L, Jackson RJ, Greenhalf W, Halloran C.   +12 more
europepmc   +1 more source