Results 101 to 110 of about 130,417 (251)

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Delayed presentation of isolated grade III pancreatic injury-a case report. [PDF]

J Surg Case Rep, 2023
Ferreira MJ, Gallardo G, Vigia E, Filipe E, Marques HP.   +4 more
europepmc   +1 more source

From Cell‐Free Transcriptomes to Single‐Cell Landscapes: Biomarker Discovery and Originating Cell Alteration Analysis via Graph Matrix Factorization

Advanced Science, EarlyView.
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang, Wenjing Zhang, Hang Wei, Shiyan Liu, Junliang Shang, Weijie Gong, Hanwen Cheng, Xiujuan Lei, Yuhui Kou, Baoguo Jiang   +9 more
wiley   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

Advanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim, Mabel Bartlett, Liyang Wang, Karl Bates, Mengdi He, Myungbo Kim, Carmel Majidi, Tzahi Cohen‐Karni   +7 more
wiley   +1 more source

Association Between Liver Function Grade and Post‐Hepatectomy Liver Failure in Patients With Hepatocellular Carcinoma: A Latent Class Analysis

Annals of Gastroenterological Surgery, EarlyView.
We retrospectively analyzed clinical data from patients who underwent hepatectomy for hepatocellular carcinoma (HCC) using LCA‐based grading system. These findings provide a new risk stratification framework for the design of precision surgery to treat patients with HCC.
Ling Liu, Jintao Zheng, Ye Wang, Chenao Yang, Jiachen Zhang, Changku Jia   +5 more
wiley   +1 more source

Prospective Feasibility Study of Laparoscopic and Robotic Distal Gastrectomy for Advanced Gastric Cancer to Verify the Safety of Surgical Proximal Margins

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Ensuring an adequate surgical proximal margin (SPM) is crucial in radical gastrectomy for gastric cancer. However, the lack of tactile feedback in laparoscopic distal gastrectomy (LDG) and robotic distal gastrectomy (RDG) poses challenges in precisely determining tumor boundaries, particularly in advanced gastric cancer, where tumor ...
Rie Makuuchi, Souya Nunobe, Naoki Ishizuka, Shinichiro Atsumi, Yoshiaki Shoji, Motonari Ri, Masaru Hayami, Tomoyuki Irino, Manabu Ohashi, Takeshi Sano   +9 more
wiley   +1 more source

A Rare Case of Paraesophageal Hernia Repair Complicated by Pancreatic Injury. [PDF]

Cureus, 2023
Varda B, Jasurda J, Haseeb A.
europepmc   +1 more source

Which Method Best Predicts Postoperative Complications: Deep Learning, Machine Learning, or Conventional Logistic Regression?

Annals of Gastroenterological Surgery, EarlyView.
Deep learning has shown promise in predicting postoperative complications, particularly when using image or time‐series data. However, on tabular clinical data such as the NCD, it often underperforms compared to conventional machine learning. Integrating multimodal data may enhance predictive accuracy and interpretability in surgical care.
Ryosuke Fukuyo, Masanori Tokunaga, Hiroyuki Yamamoto, Hideki Ueno, Yusuke Kinugasa   +4 more
wiley   +1 more source

Gut microbiota aggravates neutrophil extracellular traps-induced pancreatic injury in hypertriglyceridemic pancreatitis. [PDF]

Nat Commun, 2023
Li G, Liu L, Lu T, Sui Y, Zhang C, Wang Y, Zhang T, Xie Y, Xiao P, Zhao Z, Cheng C, Hu J, Chen H, Xue D, Chen H, Wang G, Kong R, Tan H, Bai X, Li Z, McAllister F, Li L, Sun B.   +22 more
europepmc   +1 more source

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source