Results 121 to 130 of about 274,531 (173)

Long non-coding RNA AC245100.4 for early diagnosis and prognostic assessment in acute pancreatitis: clinical value and inflammation-regulatory mechanisms. [PDF]

Front Pharmacol
Chen J, Mu Y, Yi P.
europepmc   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Extreme Hyperlipasemia in End-Stage Renal Disease Mimicking Acute Pancreatitis: A Diagnostic Pitfall. [PDF]

Cureus
Sheikh M, Casto D, Braha M, Izquierdo-Pretel G.   +3 more
europepmc   +1 more source

Effects of ketogenic and low‐carbohydrate diet on glucose and weight control in type 2 diabetes mellitus patients along with metabolome change

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Both the low‐carbohydrate diet (LCD) and the ketogenic diet (KD) positively affect body weight and glucose metabolism in type 2 diabetes. Metabolomic signatures sensitively reflect each diet and correlate with clinical improvements – distinct metabolite associations with glycated haemoglobin and weight were identified for LCD versus KD.
Yao Wang, Haozhe He, Zhenjing Lyu, Yeyang Wang, Li Chen, Junbin Liang, Cong Lin, Huanhuan Wang, Shiping Zhang, Gugen Xu, Junzhang Tian, Kejing Zeng   +11 more
wiley   +1 more source

Development of a multiplex assay for early detection of pancreatic cancer in high-risk groups. [PDF]

BMC Cancer
Pan S, Karki R, Lai LA, Creighton CJ, Brentnall TA, Brand RE, Chen R.   +6 more
europepmc   +1 more source

Reconceptualizing Dyslipidemia: Diversity of Lipid Imbalances and Their Clinical Implications; A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The traditional definition of dyslipidemia focuses on isolated lipid changes (LDL‐C, HDL‐C, triglycerides) and may not fully capture the biological complexity or clinical variability of lipid imbalances. Recent evidence challenges this narrow view, suggesting that dyslipidemia involves broader disruptions in lipid ...
Ali Mansoursamaei, Amirhossein Yadegar, Fatemeh Mohammadi, Seyed Arsalan Seyedi, Soghra Rabizadeh, Sahar Karimpour Reyhan, Alireza Esteghamati, Manouchehr Nakhjavani   +7 more
wiley   +1 more source

Tricellulin regulates the tight junctions and cytoskeleton of pancreatic acinar cells through the NF-κB pathway in hypertriglyceridemic acute pancreatitis. [PDF]

Biomed Rep
Wei G, Liang Z, Wei H, Wu Q, Wang J, Lin L, Liang Z, Yang H, Qin M.   +8 more
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Mechanistic insights into how intrapancreatic fat deposition drives the development of acute pancreatitis. [PDF]

Int J Biol Sci
Gu X, Zhang H, Lin W, Chen W, Le C, Huang Z, Liu Q, Yang J.   +7 more
europepmc   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source